Dihydro-5-nonyl-2(3H)-furanone

Base Information

• Chemical Name: Dihydro-5-nonyl-2(3H)-furanone
• CAS No.: 7370-36-7
• Molecular Formula: C₁₃H₂₄O₂
• Molecular Weight: 212.332
• DSSTox Substance ID: DTXSID50994566
• Nikkaji Number: J185.608A
• Mol file: 7370-36-7.mol

Synonyms:5-nonyl-2-tetrahydrofuranone;2(3H)-Furanone,dihydro-5-nonyl;5-nonyldihydrofuran-2(3H)-one;5-Nonyl-dihydro-furan-2-on;5-nonyl-dihydro-furan-2-one;4-tridecanolide;5-nonyldihydro-2(3H)-furanone;

Chemical Property of Dihydro-5-nonyl-2(3H)-furanone

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Boiling Point: 308.621oC at 760 mmHg
• Flash Point: 126.292oC
• PSA: 26.30000
• Density: 0.926g/cm3
• LogP: 3.83270
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 8
• Exact Mass: 212.177630004
• Heavy Atom Count: 15
• Complexity: 177

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCC1CCC(=O)O1

Technology Process of Dihydro-5-nonyl-2(3H)-furanone

There total 14 articles about Dihydro-5-nonyl-2(3H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

4-hydroxytridecanoic acid (116854-39-8) → 5-nonyldihydrofuran-2(3H)-one (7370-36-7)

Guidance literature:

at 110 - 145 ℃; for 0.5h;

Reference yield: 29.0%

C16H27NO2 (1313212-37-1) → 5-nonyldihydrofuran-2(3H)-one (7370-36-7)

Guidance literature:

With sulfuric acid; In water; at 100 ℃; for 48h;

DOI:10.1080/00397911.2010.501472

Reference yield:

lauric acid (143-07-7) + trimethylsulphonium hydroxide (17287-03-5) → gamma-dodecalactone (57084-18-1,2305-05-7) + 5-nonyldihydrofuran-2(3H)-one (7370-36-7) + 5-Hydroxy-laurinsaeuremethylester (42550-37-8) + methyl 10-hydroxydodecanoate (27512-78-3) + Methyl (+/-)-γ-hydroxy-γ-octylbutyrate (132214-85-8) + 9-Hydroxy-dodecanoic acid methyl ester (87442-15-7) + (-)-(R)-11-Hydroxydodecansaeure-methylester (109718-22-1) + methyl 6-hydroxydodecanoate (84770-43-4)

Guidance literature:

With glucose dehydrogenase from Bacillus megaterium; cytochrome P₄₅₀ monooxygenase CYP₅₀₅E₃ from Aspergillus terreus; nicotinamide adenine dinucleotide; In aq. phosphate buffer; dimethyl sulfoxide; at 25 ℃; for 24h; regioselective reaction; Enzymatic reaction;

DOI:10.1002/anie.202001055

upstream raw materials:

4-hydroxytridecanoic acid

1,4-tridecanediol

sodium diethylmalonate

furfural

Refernces

• 1、 Patel, Nandini C.,Schwarz, Jacob B.,Islam, Khondaker,Miller, Whitney,Tran, Tuan P.,Wei, Yunjing. "Improved synthesis of γ-lactones from cyclopropyl cyanoesters". . p. 2209 - 2215. Retrieved 2011/07/07.