2,3,5-Trimethylthiophene

Base Information

• Chemical Name: 2,3,5-Trimethylthiophene
• CAS No.: 1795-05-7
• Molecular Formula: C7H10S
• Molecular Weight: 126.222
• European Community (EC) Number: 217-269-7
• DSSTox Substance ID: DTXSID80170816
• Nikkaji Number: J203.192B
• Wikidata: Q72514599
• Mol file: 1795-05-7.mol

Synonyms:2,3,5-Trimethylthiophene;1795-05-7;Thiophene, 2,3,5-trimethyl-;2,3,5-trimethyl-thiophene;EINECS 217-269-7;2,4,5-trimethyl-thiophene;SCHEMBL115473;DTXSID80170816;GEO-02426;MFCD00142784;AKOS005257032;AS-77900;CS-0324136;FT-0609463;T1327;EN300-379156;T71950;A812454;W-200175

Chemical Property of 2,3,5-Trimethylthiophene

Chemical Property:

• Melting Point: -51.23°C (estimate)
• Refractive Index: 1.5120 to 1.5140
• Boiling Point: 166.564 °C at 760 mmHg
• Flash Point: 36.218 °C
• PSA: 28.24000
• Density: 0.988 g/cm³
• LogP: 2.67330
• Storage Temp.: 2-8°C
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 126.05032149
• Heavy Atom Count: 8
• Complexity: 80.5

Purity/Quality:

99% ^*data from raw suppliers

2,3,5-Trimethylthiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(S1)C)C

Technology Process of 2,3,5-Trimethylthiophene

There total 20 articles about 2,3,5-Trimethylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,5-dimethylthiophene-2-carboxaldehyde (5928-48-3) → 2,4,5-trimethylthiophene (1795-05-7)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; ethylene glycol;

DOI:10.1021/jo01156a016

Reference yield:

2,5-dimethyl-thiophene-3-carbaldehyde (26421-44-3) → 2,4,5-trimethylthiophene (1795-05-7)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; ethylene glycol;

DOI:10.1021/jo01156a016

Reference yield:

2,5-dimethyl-thiophene-3-carbaldehyde semicarbazone (26421-46-5) → 2,4,5-trimethylthiophene (1795-05-7)

Guidance literature:

With potassium hydroxide; water;

DOI:10.1021/ja01152a525

upstream raw materials:

4,5-dimethylthiophene-2-carboxaldehyde

2,5-dimethyl-thiophene-3-carbaldehyde

2,5-dimethyl-thiophene-3-carbaldehyde semicarbazone

2,3-dimethyl-2-propenyl-oxirane

Downstream raw materials:

2,4,5-trimethyl-thiophene-3-carbaldehyde

tetramethylthiophene

thiophene

2,5-DIMETHYLTHIOPHENE

Refernces

• 1、 Kates,Schauble. "Mono- and bis-carbonyl methylenation of thiolane-2,5-diones (succinic thioanhydrides)". . p. 494 - 496. Retrieved 1994.
• 2、 Gubina, T. I.,Labunskaya, V. I.,Pankratov, A. N.,Trushin, S. A.,Kharchenko, V. G.. "INVESTIGATION OF THE MECHANISM OF THE RECYCLIZATION OF FURANS TO THIOPHENES AND SELENOPHENES UNDER ACID-CATALYSIS CONDITIONS. 3. INVESTIGATION OF THE RECYCLIZATION OF HOMOLOGS AND FUNCTIONAL DERIVATIVES OF FURAN. QUANTUM-CHEMICAL CALCULATIONS OF THE OBJECTS OF THE RECYCLIZATION". . p. 1393 - 1398. Retrieved 2007/10/02.