2-AcetaMidobenzyl Alcohol

Base Information

• Chemical Name: 2-AcetaMidobenzyl Alcohol
• CAS No.: 20939-77-9
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.192
• Hs Code.: 2924299090
• Mol file: 20939-77-9.mol

Synonyms:2-Acetamidobenzyl alcohol;2-Acetylaminobenzo[b]furan;N-2-BENZOFURANYL-ACETAMIDE;Acetamide,N-2-benzofuranyl;N-acetyl-2-aminobenzyl alcohol;2-Acetamido-benzofuran;N-(BENZOFURAN-2-YL)ACETAMIDE;N-(2-(hydroxymethyl)-phenyl)acetamide;

Chemical Property of 2-AcetaMidobenzyl Alcohol

Chemical Property:

• Vapor Pressure: 6.96E-07mmHg at 25°C
• Boiling Point: 393.1°Cat760mmHg
• Flash Point: 191.5°C
• PSA: 49.33000
• Density: 1.211g/cm³
• LogP: 1.21030
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

2-AcetamidobenzylAlcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AcetaMidobenzyl Alcohol

There total 22 articles about 2-AcetaMidobenzyl Alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-Aminobenzyl alcohol (5344-90-1) + acetyl chloride (75-36-5) → 2-acetamidobenzyl alcohol (20939-77-9)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2003.11.118

Reference yield: 93.0%

2-Nitrobenzyl alcohol (612-25-9) + ethyl acetate (141-78-6) → 2-acetamidobenzyl alcohol (20939-77-9)

Guidance literature:

2-Nitrobenzyl alcohol; With sodium tetrahydroborate; In ethyl acetate;

ethyl acetate; With bis(dimethylglyoximato)copper(II); for 2.83333h; Reflux;

DOI:10.1002/jccs.201800325

Reference yield: 92.0%

ethyl acetate (141-78-6) + 2-nitro-benzaldehyde (552-89-6) → 2-acetamidobenzyl alcohol (20939-77-9)

Guidance literature:

2-nitro-benzaldehyde; With sodium tetrahydroborate; In ethyl acetate;

ethyl acetate; With bis(dimethylglyoximato)copper(II); for 3h; Reflux;

DOI:10.1002/jccs.201800325

upstream raw materials:

2-aminobenzyl acetate

N-acetyl-O-acetyl-2-aminobenzyl alcohol

aluminum isopropoxide

2-Aminobenzyl alcohol

Downstream raw materials:

o-acetylaminobenzyl benzoate

N-(2-formylphenyl)acetamide

N-(2-fluorophenyl)acetamide

N-(2-(hydroxy(2-nitrophenyl)methyl)phenyl)acetamide

Refernces

• 1、 Zeynizadeh, Behzad,Mohammad Aminzadeh, Farkhondeh,Mousavi, Hossein. "Chemoselective reduction of nitroarenes, N-acetylation of arylamines, and one-pot reductive acetylation of nitroarenes using carbon-supported palladium catalytic system in water". . p. 3289 - 3312. Retrieved 2021/05/11.
• 2、 -. "NOVEL IMIDAZO-PYRAZINE DERIVATIVES". Page/Page column 45; 98. . Retrieved 2021/12/31.