5-Ethyl-2-furaldehyde

Base Information

• Chemical Name: 5-Ethyl-2-furaldehyde
• CAS No.: 23074-10-4
• Molecular Formula: C7H8O2
• Molecular Weight: 124.139
• Hs Code.: 29321900
• European Community (EC) Number: 245-411-8
• UNII: YYH2MYA6S7
• DSSTox Substance ID: DTXSID80177643
• Nikkaji Number: J318.396C
• Mol file: 23074-10-4.mol

Synonyms:5-Ethyl-2-furaldehyde;23074-10-4;5-ethylfuran-2-carbaldehyde;2-Furancarboxaldehyde, 5-ethyl-;5-Ethyl-furan-2-carbaldehyde;5-Ethylfurfural;5-ethylfuran-2-carboxaldehyde;EINECS 245-411-8;MFCD00030605;2-Furancarboxaldehyde,5-ethyl-;5-ethylfurfuraldehyde;YYH2MYA6S7;2-Furaldehyde, 5-ethyl-;5-ethyl-2-furancarboxaldehyde;SCHEMBL157526;5-Ethyl-2-furaldehyde, 98%;DTXSID80177643;GEO-01349;AKOS000295601;SB61437;AS-47636;CS-0204240;FT-0620371;EN300-51261;F14735;A816555;W-200239;Z274774406

Chemical Property of 5-Ethyl-2-furaldehyde

Chemical Property:

• Appearance/Colour: clear colorless to dark yellow liquid
• Vapor Pressure: 0.418mmHg at 25°C
• Refractive Index: n20/D 1.522(lit.)
• Boiling Point: 195.5 °C at 760 mmHg
• Flash Point: 65.6 °C
• PSA: 30.21000
• Density: 1.063 g/cm³
• LogP: 1.65450
• Storage Temp.: 0-6°C
• Sensitive.: Air Sensitive
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 124.052429494
• Heavy Atom Count: 9
• Complexity: 101

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Ethyl-2-furaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC1=CC=C(O1)C=O
• Uses: 5-Ethyl-2-furaldehyde was used in the synthesis of N-(tert-butoxycarbonyl)-3-(benzoxazol-5-yl)alanine methyl ester derivatives.

Technology Process of 5-Ethyl-2-furaldehyde

There total 7 articles about 5-Ethyl-2-furaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-ethylfuran (3208-16-0) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 5-ethylfurfural (23074-10-4)

Guidance literature:

With trichlorophosphate; for 1.5h; O deg C to room temp.;

DOI:10.1021/ja00201a066

Reference yield: 78.0%

5-ethylfurfuraldehyde oxime (89114-36-3) → 5-ethylfurfural (23074-10-4)

Guidance literature:

With benzeneselenic anhydride; In dichloromethane;

DOI:10.1016/S0040-4039(00)94107-8

Reference yield:

C5H3LiNO2(1-)*Li(1+) → 5-ethylfurfural (23074-10-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / tetrahydrofuran; hexane; various solvent(s) / -78 - 25 °C

2: 78 percent / phenylselenic anhydride / CH₂Cl₂

With benzeneselenic anhydride; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1016/S0040-4039(00)94107-8

upstream raw materials:

2-ethylfuran

hydrogen cyanide

N,N-dimethyl-formamide

5-ethylfurfuraldehyde oxime

Downstream raw materials:

2-ethyl-5-methylfuran

Refernces

• 1、 Kuo,Shih. "A new method for preparation of 3-hydroxypyridines from furfurylamines by photooxygenation". . p. 181 - 183. Retrieved 2007/10/02.
• 2、 Cabares, Jacques,Mavoungou-Gomes, Louis. "Preparation des acides alkyl et arylalkyl-5 methyl-2 benzofurannedicarboxyliques-6,7. Application a la synthese de derives de nouveaux heterocycles". . p. 401 - 412. Retrieved 2007/10/02.