Benzeneacetic acid, 3,4-dimethoxy-2-(phenylmethoxy)-

Base Information Edit

Chemical Name:Benzeneacetic acid, 3,4-dimethoxy-2-(phenylmethoxy)-
CAS No.:79659-43-1
Molecular Formula:C17H18O5
Molecular Weight:302.327
Hs Code.:
DSSTox Substance ID:DTXSID60361649
Wikidata:Q82144068
Mol file:79659-43-1.mol

Synonyms:Benzeneacetic acid, 3,4-dimethoxy-2-(phenylmethoxy)-;79659-43-1;DTXSID60361649

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzeneacetic acid, 3,4-dimethoxy-2-(phenylmethoxy)- Edit

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:302.11542367
Heavy Atom Count:22
Complexity:340

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)CC(=O)O)OCC2=CC=CC=C2)OC

Technology Process of Benzeneacetic acid, 3,4-dimethoxy-2-(phenylmethoxy)-

There total 4 articles about Benzeneacetic acid, 3,4-dimethoxy-2-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 90158-03-5
4-<2-(2-benzyloxy-3,4-dimethoxyphenyl)-1-thioxoethyl>morpholine

: 79659-43-1
2'-benzyloxy-3',4'-dimethoxyphenylacetic acid

Guidance literature:: With hydrogenchloride; potassium hydroxide; In ethanol; water; for 9h; Heating;
DOI:10.1248/cpb.33.5316

Reference yield:

: 56774-68-6
2'-benzyloxy-3',4'-dimethoxyacetophenone

: 79659-43-1
2'-benzyloxy-3',4'-dimethoxyphenylacetic acid

Guidance literature:: With hydrogenchloride; sodium methylate; thallium(III) nitrate; Yield given. Multistep reaction; 1.) methylene chloride, room temperature, 1 h; 2.) methanol, H₂O, overnight;
DOI:10.1002/jhet.5570180410

Reference yield:

: 5396-18-9
2'-hydroxy-3',4'-dimethoxyacetophenone

: 79659-43-1
2'-benzyloxy-3',4'-dimethoxyphenylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 6.4 g / K₂CO₃ / acetone / Heating; overnight

2: 1.) Tl(NO₃)3 on Montmorillinite clay; 2.) sodium methoxide; aq. HCl / 1.) methylene chloride, room temperature, 1 h; 2.) methanol, H₂O, overnight

With hydrogenchloride; sodium methylate; potassium carbonate; thallium(III) nitrate; In acetone;
DOI:10.1002/jhet.5570180410