(Z)-2-(MethoxyiMino)-3-oxobutanoic Acid Methyl Ester

Base Information

• Chemical Name: (Z)-2-(MethoxyiMino)-3-oxobutanoic Acid Methyl Ester
• CAS No.: 80350-55-6
• Molecular Formula: C6H9NO4
• Molecular Weight: 159.14000
• Mol file: 80350-55-6.mol

Synonyms:Hexadecanoic acid,2-methoxy-,methyl ester;methyl 2-methoxyimino-3-oxobutyrate;methyl 3-oxo-2-methoxyiminobutyrate;2-Methoxyhexadecanoic acid methyl ester;methyl 2-methoxyimino-3-oxobutanoate;

Chemical Property of (Z)-2-(MethoxyiMino)-3-oxobutanoic Acid Methyl Ester

Chemical Property:

• PSA: 64.96000
• LogP: -0.24920
• Solubility.: Chloroform, Dichloromethane, Methanol

Purity/Quality:

97% ^*data from raw suppliers

(Z)-2-(Methoxyimino)-3-oxobutanoicAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (Z)-2-(Methoxyimino)-3-oxobutanoic Acid Methyl Ester (cas# 80350-55-6) is a compound useful in organic synthesis.

Technology Process of (Z)-2-(MethoxyiMino)-3-oxobutanoic Acid Methyl Ester

There total 2 articles about (Z)-2-(MethoxyiMino)-3-oxobutanoic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

methyl (Z)-2-(hydroxyimino)-3-oxobutanoate (86459-32-7) + methyl iodide (74-88-4) → methyl 3-oxo-2-methoxyiminobutyrate (80350-55-6)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 25 ℃; for 24h; purified by flash chrromy. on SiO₂;

DOI:10.7164/antibiotics.50.237

Reference yield:

→ methyl 3-oxo-2-methoxyiminobutyrate (80350-55-6)

Guidance literature:

Reference yield: 56.0%

methyl 3-oxo-2-methoxyiminobutyrate (80350-55-6) → (Z)-5-methyl-2H-pyrazole-3,4-dione-3-(O-methyloxime) (404910-04-9,406938-87-2) + dimethyl 2,2'-di(methoxyimino)-3,3'-azinodibutanoate

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 24h;

DOI:10.1023/A:1013160902476

upstream raw materials:

methyl (Z)-2-(hydroxyimino)-3-oxobutanoate

methyl iodide

Downstream raw materials:

(Z)-5-methyl-2H-pyrazole-3,4-dione-3-(O-methyloxime)

Refernces

• 1、 -. "Cephalosporin derivatives". . . Retrieved 2008/06/13.
• 2、 -. "[3-Heterocyclic-7-(2-methoxyimino-2-aminothiazolyl) acetamido]cephalosporins". . . Retrieved 2008/06/13.