Bis(2-hydroxyethyl) succinate

Base Information

• Chemical Name: Bis(2-hydroxyethyl) succinate
• CAS No.: 10283-83-7
• Molecular Formula: C8H14O6
• Molecular Weight: 206.196
• Hs Code.: 2918199090
• European Community (EC) Number: 233-631-7
• DSSTox Substance ID: DTXSID80145529
• Nikkaji Number: J236.742D
• Wikidata: Q83010099
• Mol file: 10283-83-7.mol

Synonyms:Bis(2-hydroxyethyl) succinate;bis(2-hydroxyethyl) butanedioate;10283-83-7;EINECS 233-631-7;SCHEMBL475320;DTXSID80145529;Succinic acid bis(2-hydroxyethyl) ester;Butanedioic acid, bis(2-hydroxyethyl) ester;1,4-BIS(2-HYDROXYETHYL) BUTANEDIOATE

Chemical Property of Bis(2-hydroxyethyl) succinate

Chemical Property:

• Vapor Pressure: 1.23E-06mmHg at 25°C
• Refractive Index: 1.474
• Boiling Point: 360 °C at 760 mmHg
• PKA: 13.57±0.10(Predicted)
• Flash Point: 142.6 °C
• PSA: 93.06000
• Density: 1.268 g/cm³
• LogP: -1.16240
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 206.07903816
• Heavy Atom Count: 14
• Complexity: 159

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(=O)OCCO)C(=O)OCCO

Technology Process of Bis(2-hydroxyethyl) succinate

There total 2 articles about Bis(2-hydroxyethyl) succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

succinic acid (110-15-6) + ethylene glycol (107-21-1) → bis(2-hydroxyethyl) butanedioate (10283-83-7)

Guidance literature:

With sulfuric acid; at 70 ℃; for 15h;

DOI:10.1021/ja1008932

Reference yield:

oxirane (75-21-8,99932-75-9) + succinic acid (110-15-6) → bis(2-hydroxyethyl) butanedioate (10283-83-7)

Guidance literature:

at 80 - 90 ℃;

Reference yield:

bis(2-hydroxyethyl) butanedioate (10283-83-7) + 4-nitro-benzoyl chloride (122-04-3) → succinic acid bis-[2-(4-nitro-benzoyloxy)-ethyl ester]

Guidance literature:

With pyridine;

upstream raw materials:

oxirane

succinic acid

ethylene glycol

Refernces

• 1、 -. "REVERSIBLE LINKERS AND USE THEREOF". Paragraph 00121. . Retrieved 2019/04/10.
• 2、 Kryger, Matthew J.,Ong, Mitchell T.,Odom, Susan A.,Sottos, Nancy R.,White, Scott R.,Martinez, Todd J.,Moore, Jeffrey S.. "Masked cyanoacrylates unveiled by mechanical force". supporting information; experimental part. p. 4558 - 4559. Retrieved 2010/06/01.