Technology Process of 2(1H)-Isoquinolinepropanoic acid,
3,4-dihydro-6-[3-[(3-hydroxypropyl)amino]-2-nitrophenoxy]-1-oxo-, ethyl
ester
There total 6 articles about 2(1H)-Isoquinolinepropanoic acid,
3,4-dihydro-6-[3-[(3-hydroxypropyl)amino]-2-nitrophenoxy]-1-oxo-, ethyl
ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine;
In
1,2-dimethoxyethane;
for 2h;
Heating / reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: caesium carbonate / N,N-dimethyl-formamide / 80 °C
2: ethanol / Reflux
With
caesium carbonate;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2008.11.074
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 10% palladium on activated carbon; hydrogen / ethanol / 760.05 Torr
2: caesium carbonate / N,N-dimethyl-formamide / 80 °C
3: ethanol / Reflux
With
10% palladium on activated carbon; hydrogen; caesium carbonate;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2008.11.074
