2-morpholin-4-ylacetohydrazide

Base Information

• Chemical Name: 2-morpholin-4-ylacetohydrazide
• CAS No.: 770-17-2
• Molecular Formula: C6H13N3O2
• Molecular Weight: 159.188
• Hs Code.: 2934999090
• Mol file: 770-17-2.mol

Synonyms:2-morpholinoacetohydrazide;N-amino-2-morpholin-4-ylacetamide;N-morpholinylacetic acid hydrazide;morpholin-4-yl-acetic acid hydrazide;

Chemical Property of 2-morpholin-4-ylacetohydrazide

Chemical Property:

• Vapor Pressure: 4.18E-05mmHg at 25°C
• Boiling Point: 351.2°Cat760mmHg
• PKA: 13.01±0.18(Predicted)
• Flash Point: 166.2°C
• PSA: 67.59000
• Density: 1.172g/cm³
• LogP: -0.66240
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%min ^*data from raw suppliers

2-Morpholin-4-ylacetohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-morpholin-4-ylacetohydrazide

There total 3 articles about 2-morpholin-4-ylacetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 2-morpholin-4-ylacetate (35855-10-8) → 2-(4-morpholinyl)acetylhydrazine (770-17-2)

Guidance literature:

With hydrazine; In ethanol; at 90 ℃; for 18h;

Reference yield: 68.0%

→ 2-(4-morpholinyl)acetylhydrazine (770-17-2)

Guidance literature:

Reference yield:

N-morpholylacetic acid ethyl ester (3235-82-3) → 2-(4-morpholinyl)acetylhydrazine (770-17-2)

Guidance literature:

With hydrazine hydrate;

upstream raw materials:

N-morpholylacetic acid ethyl ester

methyl 2-morpholin-4-ylacetate

Downstream raw materials:

4-(2-methoxy-phenyl)-1-(morpholin-4-yl-acetyl)-thiosemicarbazide

1-(morpholin-4-yl-acetyl)-4-m-tolyl-thiosemicarbazide

N-[2-(2-morpholinoacetyl)hydrazinocarbonothioyl]benzamide

2-(morpholin-4-ylmethyl)-7-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-c]pyrimidin-5-ol

Refernces

• 1、 -. "Hetero-aromatic compound and its use in medicine". Paragraph 0989; 1010-1012. . Retrieved 2019/07/04.
• 2、 -. "NUCLEAR TRANSPORT MODULATORS AND USES THEREOF". Paragraph 00266. . Retrieved 2013/12/03.