Carbonic acid, 2-(2-(4-bromophenyl)-4-morpholinyl)ethyl ethyl ester, hydrochloride

Base Information

• Chemical Name: Carbonic acid, 2-(2-(4-bromophenyl)-4-morpholinyl)ethyl ethyl ester, hydrochloride
• CAS No.: 185759-08-4
• Molecular Formula: C15H21BrClNO4
• Molecular Weight: 394.6885
• DSSTox Substance ID: DTXSID50939992
• Mol file: 185759-08-4.mol

Synonyms:185759-08-4;Carbonic acid, 2-(2-(4-bromophenyl)-4-morpholinyl)ethyl ethyl ester, hydrochloride;2-[2-(4-bromophenyl)morpholin-4-yl]ethyl ethyl carbonate;hydrochloride;Carbonic acid, 2-(2-(4-bromophenyl)-4-morpholinyl)ethyl ethyl ester, h ydrochloride;C15H20BrNO4.ClH;DTXSID50939992;PATPHRMTNCXVRC-UHFFFAOYSA-N;C15-H20-Br-N-O4.Cl-H;LS-51927;2-[2-(4-Bromophenyl)morpholin-4-yl]ethyl ethyl carbonate--hydrogen chloride (1/1)

Chemical Property of Carbonic acid, 2-(2-(4-bromophenyl)-4-morpholinyl)ethyl ethyl ester, hydrochloride

Chemical Property:

• Vapor Pressure: 1.4E-07mmHg at 25°C
• Boiling Point: 429.5°Cat760mmHg
• Flash Point: 213.5°C
• PSA: 48.00000
• Density: g/cm³
• LogP: 3.73540
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 393.03425
• Heavy Atom Count: 22
• Complexity: 321

Purity/Quality:

2-[2-(4-BROMOPHENYL)-4-MORPHOLINYL]ETHYL ETHYL CARBONATE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)OCCN1CCOC(C1)C2=CC=C(C=C2)Br.Cl

Technology Process of Carbonic acid, 2-(2-(4-bromophenyl)-4-morpholinyl)ethyl ethyl ester, hydrochloride

There total 2 articles about Carbonic acid, 2-(2-(4-bromophenyl)-4-morpholinyl)ethyl ethyl ester, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

chloroformic acid ethyl ester (541-41-3) + 2-[2-(4-Bromo-phenyl)-morpholin-4-yl]-ethanol (234089-73-7) → Carbonic acid 2-[2-(4-bromo-phenyl)-morpholin-4-yl]-ethyl ester ethyl ester; hydrochloride (185759-08-4)

Guidance literature:

In benzene;

DOI:10.1016/S0223-5234(97)89855-8

Reference yield:

1-(4-bromophenyl)-2-chloroethan-1-one (4209-02-3) → Carbonic acid 2-[2-(4-bromo-phenyl)-morpholin-4-yl]-ethyl ester ethyl ester; hydrochloride (185759-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: formic acid / 15 h / 180 °C

2: 52 percent / benzene

With formic acid; In benzene;

DOI:10.1016/S0223-5234(97)89855-8

upstream raw materials:

chloroformic acid ethyl ester

2-[2-(4-Bromo-phenyl)-morpholin-4-yl]-ethanol

1-(4-bromophenyl)-2-chloroethan-1-one

Refernces