2,5-DIPHENYLPYRAZINE

Base Information

• Chemical Name: 2,5-DIPHENYLPYRAZINE
• CAS No.: 5398-63-0
• Molecular Formula: C16H12N2
• Molecular Weight: 232.285
• Hs Code.: 2933990090
• Mol file: 5398-63-0.mol

Synonyms:2,5-diphenylpyrazine;

Chemical Property of 2,5-DIPHENYLPYRAZINE

Chemical Property:

• Vapor Pressure: 2.44E-06mmHg at 25°C
• Refractive Index: 1.61
• Boiling Point: 403 °C at 760 mmHg
• Flash Point: 153.2 °C
• PSA: 25.78000
• Density: 1.125 g/cm³
• LogP: 3.81060

Purity/Quality:

99% ^*data from raw suppliers

2,5-DIPHENYLPYRAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-DIPHENYLPYRAZINE

There total 83 articles about 2,5-DIPHENYLPYRAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N,N-bis(tert-butoxycarbonyl)-2,5-diphenyl-[1,4]-dihydropyrazine (1059631-24-1) → 2,5-diphenylpyrazine (5398-63-0)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tet.2008.06.080

Reference yield: 99.0%

Phenylglycinol (20989-17-7,56613-80-0,71006-16-1,7568-92-5,188586-38-1) → 2,5-diphenylpyrazine (5398-63-0)

Guidance literature:

With C₃₉H₃₁BMnNO₂P₂; potassium hydride; In toluene; at 150 ℃; for 24h; Reagent/catalyst; Solvent; Temperature; Catalytic behavior;

DOI:10.1021/acscatal.8b02208

Reference yield: 89.0%

(Z)-2-bromo-1-phenylethylene acetate (99511-02-1) → 2,5-diphenylpyrazine (5398-63-0)

Guidance literature:

With ammonium formate; In N,N-dimethyl-formamide; at 120 ℃; for 6h; Reagent/catalyst; Solvent; Temperature; Time; regioselective reaction; Schlenk technique;

DOI:10.1039/c3ob41164h

upstream raw materials:

2-diazo-acetophenone

ethanol

3,6-diphenyl-1,2-dihydro-pyrazine

3,6-diphenyl-2,5-dihydropyrazine

Downstream raw materials:

trans-2,5-Diphenyl-piperazin

3,6-diphenyl-2,5-dihydropyrazine

2,5-diphenylpyrazine 1-oxide

2-amino-3,6-diphenylpyrazine

Refernces

• 1、 -. "PHOSPHINE FREE COBALT BASED CATALYST, PROCESS FOR PREPARATION AND USE THEREOF". Paragraph 0069; 0158-0159. . Retrieved 2020/12/29.
• 2、 Daw, Prosenjit,Kumar, Amit,Espinosa-Jalapa, Noel Angel,Diskin-Posner, Yael,Ben-David, Yehoshoa,Milstein, David. "Synthesis of Pyrazines and Quinoxalines via Acceptorless Dehydrogenative Coupling Routes Catalyzed by Manganese Pincer Complexes". . p. 7734 - 7741. Retrieved 2018/08/03.