2-amino-3,6-diphenylpyrazine

Base Information

• Chemical Name: 2-amino-3,6-diphenylpyrazine
• CAS No.: 41270-72-8
• Molecular Formula: C₁₆H₁₃N₃
• Molecular Weight: 247.299
• Mol file: 41270-72-8.mol

Synonyms:2-amino-3,6-diphenylpyrazine

Chemical Property of 2-amino-3,6-diphenylpyrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-3,6-diphenylpyrazine

There total 10 articles about 2-amino-3,6-diphenylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-Chloro-3,6-diphenylpyrazine (41270-64-8) → 2-amino-3,6-diphenylpyrazine (41270-72-8)

Guidance literature:

With benzamide; potassium carbonate; at 180 - 230 ℃; for 1h;

Reference yield: 37.0%

acetamide (60-35-5) + 2-Chloro-3,6-diphenylpyrazine (41270-64-8) → 2-amino-3,6-diphenylpyrazine (41270-72-8) + N-(3,6-Diphenyl-pyrazin-2-yl)-acetamide (74152-21-9)

Guidance literature:

With potassium carbonate; for 14h; Heating;

Reference yield: 35.0%

2-azido-3,6-diphenylpyrazine (76849-27-9) → 2-amino-3,6-diphenylpyrazine (41270-72-8)

Guidance literature:

With ammonium hydroxide; hydrogen; palladium on activated charcoal; In 1,2-dimethoxyethane; for 2.5h; Ambient temperature; Parr hydrogenation apparatus;

DOI:10.1055/s-1994-25607

upstream raw materials:

2-azido-3,6-diphenylpyrazine

acetamide

2-Chloro-3,6-diphenylpyrazine

2,5-diphenylpyrazine

Downstream raw materials:

3,6-diphenylpyrazin-2(1H)-one

Refernces

• 1、 Watanabe, Tokuhiro,Kikuchi, Etsuko,Tamura, Wataru,Akita, Yasuo,Tsutsui, Mayumi,Ohta, Akihiro. "A SIMPLE METHOD FOR THE PREPARATION OF SOME AMINO N-HETEROAROMATICS". . p. 287 - 290. Retrieved 2007/10/02.