Formic-d acid

Base Information

• Chemical Name: Formic-d acid
• CAS No.: 917-71-5
• Molecular Formula: CHDO2
• Molecular Weight: 47.0177
• Hs Code.: 2845901090
• European Community (EC) Number: 695-499-0
• Nikkaji Number: J208.516J
• Mol file: 917-71-5.mol

Synonyms:Formic-d acid;917-71-5;Formic Acid C-d;deuterioformic acid;Formic Acid C-d 98atom%D;deuteroformic acid;Formic-d acid, 95 wt% in Water;MFCD00059016;Formic-d acid(6CI,7CI,8CI,9CI);F0198;F1159;T73068;Formic-d acid, 95 wt. % in H2O, 98 atom % D

Chemical Property of Formic-d acid

Chemical Property:

• Melting Point: 8.2-8.4 °C
• Refractive Index: n20/D 1.369
• Boiling Point: 100.6 °C at 760 mmHg
• Flash Point: 29.9 °C
• PSA: 37.30000
• Density: 1.179 g/cm³
• LogP: 0.33670
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 47.011756048
• Heavy Atom Count: 3
• Complexity: 10.3

Purity/Quality:

98%Min ^*data from raw suppliers

FormicAcid-d(<5%H2O) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 35-10
• Safety Statements: 23-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)O
• Isomeric SMILES: [2H]C(=O)O
• Uses: Formic Acid-d is labelled Formic Acid (F692900). Formic Acid (F692900) is used as a potential energy source in the preparation of fuel cells. Also used in chemical synthesis of various anti-inflammatory and anti-microbial agents.

Technology Process of Formic-d acid

There total 9 articles about Formic-d acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

carbon dioxide (124-38-9,18923-20-1) + 1,2-diphenyltetramethyldisilane (1145-98-8) → deuterated formic acid (917-71-5) + deuterio(dimethyl)phenylsilane (22034-19-1)

Guidance literature:

With tetrabutyl ammonium fluoride; water-d2; In dimethyl sulfoxide; at 80 ℃; for 24h;

DOI:10.1246/cl.150654

Reference yield:

C7H5(2)HN2O3 → deuterated formic acid (917-71-5) + 2-nitro-aniline (88-74-4)

Guidance literature:

acetylcholinesterase; at 25 ℃; Rate constant; Kinetics; Thermodynamic data; 0.1 M sodium phosphate buffer, 0.1 N NaCl, 2 percent CH3CN; isotope effect, ΔH(excit.), ΔS(excit.);

DOI:10.1021/ja00235a037

Reference yield:

n-Octadecanal (638-66-4) → deuterated formic acid (917-71-5) + hepatdecane (629-78-7)

Guidance literature:

With 1,4-dihydronicotinamide adenine dinucleotide; Prochlorococcus marinus MIT₉₃₁₃ aldehyde decarbonylase; water; phenazine methosulfate; In dimethyl sulfoxide; at 37 ℃; for 0.5h;

DOI:10.1002/anie.201101552

upstream raw materials:

n-Octadecanal

2(²H)-β-D-glucospyranose

carbon dioxide

1,2-diphenyltetramethyldisilane

Downstream raw materials:

carbon dioxide

deuterium

hydrogen

dihydrogen peroxide

Refernces

• 1、 Yang, Luo,Lin, Jie,Kang, Lei,Zhou, Wang,Ma, Da-You. "Lewis Acid-Catalyzed Reductive Amination of Aldehydes and Ketones with N,N-Dimethylformamide as Dimethylamino Source, Reductant and Solvent". supporting information. p. 485 - 490. Retrieved 2018/01/15.
• 2、 Gazi, Sarifuddin,Hung Ng, Wilson Kwok,Ganguly, Rakesh,Putra Moeljadi, Adhitya Mangala,Hirao, Hajime,Soo, Han Sen. "Selective photocatalytic C-C bond cleavage under ambient conditions with earth abundant vanadium complexes". . p. 7130 - 7142. Retrieved 2015/11/24.