2,6-dimethyl-N-[(E)-phenylmethylidene]aniline

Base Information

• Chemical Name: 2,6-dimethyl-N-[(E)-phenylmethylidene]aniline
• CAS No.: 3096-95-5
• Molecular Formula: C15H15 N
• Molecular Weight: 209.291
• Hs Code.: 2925290090
• Mol file: 3096-95-5.mol

Synonyms:2,6-Xylidine,N-benzylidene- (6CI,7CI,8CI); N-Benzylidene-2,6-dimethylaniline;N-Benzylidene-2,6-xylidine

Chemical Property of 2,6-dimethyl-N-[(E)-phenylmethylidene]aniline

Chemical Property:

• Vapor Pressure: 0.000373mmHg at 25°C
• Boiling Point: 328°Cat760mmHg
• PKA: 3.50±0.50(Predicted)
• Flash Point: 144.2°C
• PSA: 12.36000
• Density: 0.95g/cm³
• LogP: 4.05400

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-dimethyl-N-[(E)-phenylmethylidene]aniline

There total 11 articles about 2,6-dimethyl-N-[(E)-phenylmethylidene]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2,6-dimethylaniline (87-62-7) + benzyl alcohol (100-51-6,185532-71-2) → 2,6-dimethyl-N-(benzylidene)aniline (3096-95-5)

Guidance literature:

With C₂₈H₂₇ClN₂Ru; caesium carbonate; In neat (no solvent); at 90 ℃; for 6.5h; Solvent; Sonication;

DOI:10.1002/aoc.5200

Reference yield: 85.0%

2,6-dimethylaniline (87-62-7) + benzylamine (100-46-9) → 2,6-dimethyl-N-(benzylidene)aniline (3096-95-5)

Guidance literature:

With C₆₂H₇₂CuN₂O₆; oxygen; In acetonitrile; at 25 ℃; for 6h; under 25.8581 Torr;

DOI:10.1021/acscatal.9b02326

Reference yield: 85.0%

4,4'-(phenylmethylene)bismorpholine (6425-08-7) + 2,6-dimethylaniline (87-62-7) → 2,6-dimethyl-N-(benzylidene)aniline (3096-95-5)

Guidance literature:

With acetic acid; at 50 - 60 ℃; for 1h;

upstream raw materials:

benzaldehyde

2,6-dimethylaniline

2,6-dimethylphenyl isonitrile

diphenylzinc

Downstream raw materials:

3-(2,6-dimethyl-phenyl)-6-ethylsulfanyl-2-phenyl-2,3-dihydro-[1,3,5]thiadiazine-4-thione

3,3-Dichloro-1-(2,6-dimethyl-phenyl)-4-phenyl-azetidin-2-one

3-(2,6-Dimethylphenyl)-N-(phenoxycarbonyl)-4-phenyl-1,3-thiazetidin-2-imin

2-hydroxy-2-phenylacetophenone

Refernces

• 1、 Jangir, Ritambhara,Ansari, Mursaleem,Kaleeswaran, Dhananjayan,Rajaraman, Gopalan,Palaniandavar, Mallayan,Murugavel, Ramaswamy. "Unprecedented Copper(II) Complex with a Topoquinone-like Moiety as a Structural and Functional Mimic for Copper Amine Oxidase: Role of Copper(II) in the Genesis and Amine Oxidase Activity". . p. 10940 - 10950. Retrieved 2019/11/13.
• 2、 Bhattacharjee, Jayeeta,Sachdeva, Mitali,Panda, Tarun K.. "Lanthanides Mediated Oxidative Cross Coupling of Benzylalcohol and Various Amines to Form Corresponding Imines". supporting information. p. 937 - 940. Retrieved 2016/09/03.