1-Fluoro-4-nitronaphthalene

Base Information

• Chemical Name: 1-Fluoro-4-nitronaphthalene
• CAS No.: 341-92-4
• Molecular Formula: C10H6FNO2
• Molecular Weight: 191.162
• Hs Code.: 2904909090
• Mol file: 341-92-4.mol

Synonyms:1-Fluoro-4-nitronaphthalene;4-Nitro-1-fluoronaphthalene;NSC 94705;

Chemical Property of 1-Fluoro-4-nitronaphthalene

Chemical Property:

• Vapor Pressure: 0.000852mmHg at 25°C
• Melting Point: 80 °C
• Refractive Index: 1.645
• Boiling Point: 314.6 °C at 760 mmHg
• Flash Point: 144.1 °C
• PSA: 45.82000
• Density: 1.369 g/cm³
• LogP: 3.41030
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

1-Fluoro-4-nitronaphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Fluoro-4-nitronaphthalene

There total 6 articles about 1-Fluoro-4-nitronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-nitro-1-naphthyldiazoniumtetrafluoroborate → 1-fluoro-4-nitronaphthalene (341-92-4)

Guidance literature:

In xylenes; for 1h; Heating / reflux;

Reference yield: 41.0%

4-fluoro-1-naphthoic acid (573-03-5) → 1-fluoro-4-nitronaphthalene (341-92-4)

Guidance literature:

With dipotassium peroxodisulfate; bismuth (III) nitrate pentahydrate; In acetonitrile; at 130 ℃; for 24h; Sealed tube;

DOI:10.1016/j.poly.2019.04.005

Reference yield: 25.0%

1-Fluoronaphthalene (321-38-0) → 1-fluoro-4-nitronaphthalene (341-92-4)

Guidance literature:

With sulfuric acid; nitric acid; Inert atmosphere;

DOI:10.1021/jo2015328

upstream raw materials:

1-Fluoronaphthalene

1-amino-4-nitronaphthalene

nitric acid

acetic acid

Downstream raw materials:

4-Fluoro-1-aminonaphthalene

N-(4-fluoro-[1]naphthyl)-benzamide

N-methyl-4-nitro-α-naphthylamine

5-Benzyloxy-1-methoxy-4-(4-nitro-naphthalen-1-yloxy)-naphthalene

Refernces

• 1、 Agasti, Soumitra,Maiti, Siddhartha,Maity, Soham,Anniyappan,Talawar,Maiti, Debabrata. "Bismuth nitrate as a source of nitro radical in ipso-nitration of carboxylic acids". . p. 120 - 124. Retrieved 2019/05/22.
• 2、 -. "FLUORINATED PHENYL-NAPHTHALENYL-UREA COMPOUNDS AS INHIBITORS OF CYTOKINES INVOLVED IN INFLAMMATORY PROCESSES". Page 38-39. . Retrieved 2010/02/06.