2,4-dimethoxy-N-phenylaniline

Base Information

• Chemical Name: 2,4-dimethoxy-N-phenylaniline
• CAS No.: 90043-09-7
• Molecular Formula: C14H15NO2
• Molecular Weight: 229.279
• DSSTox Substance ID: DTXSID80545762
• Nikkaji Number: J195.961A
• Wikidata: Q82423366
• Mol file: 90043-09-7.mol

Synonyms:2,4-dimethoxy-N-phenylaniline;90043-09-7;N-phenyl-2,4-dimethoxyaniline;SCHEMBL10785269;DTXSID80545762;PMGRJBUVIQOZNC-UHFFFAOYSA-N;(2,4-dimethoxy-phenyl)-phenyl-amine;SB79850

Chemical Property of 2,4-dimethoxy-N-phenylaniline

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 229.110278721
• Heavy Atom Count: 17
• Complexity: 216

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1)NC2=CC=CC=C2)OC

Technology Process of 2,4-dimethoxy-N-phenylaniline

There total 7 articles about 2,4-dimethoxy-N-phenylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2,4-Dimethoxyaniline (2735-04-8,161687-55-4) + phenylboronic acid (98-80-6) → N-phenyl-2,4-dimethoxyaniline (90043-09-7)

Guidance literature:

With copper immobilized at polyimide covalent organic framework; In methanol; water; at 20 ℃; for 8h;

DOI:10.1039/c8gc02611d

Reference yield: 78.0%

2,4-dimethoxyphenyllead triacetate (36896-61-4) + aniline (62-53-3) → N-phenyl-2,4-dimethoxyaniline (90043-09-7)

Guidance literature:

copper(I) acetate; In dichloromethane; for 2h;

DOI:10.1016/S0040-4039(00)99469-3

Reference yield: 47.0%

benzotriazol-1-ol (2592-95-2) + 2,4-Dimethoxyaniline (2735-04-8,161687-55-4) → N-phenyl-2,4-dimethoxyaniline (90043-09-7)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 130 ℃; for 15h;

DOI:10.1007/s10562-018-2580-4

upstream raw materials:

2,4-dimethoxyphenyllead triacetate

aniline

phenyllead(IV) triacetate

2,4-Dimethoxyaniline

Refernces

• 1、 -. "A spiral two wuwu kinds the structure of the hole transporting material, synthesis and use thereof". Paragraph 0031-0032. . Retrieved 2019/05/04.
• 2、 Barton, Derek H. R.,Donnelly, Dervilla, M. X.,Finet, Jean-Pierre,Guiry, Patrick J.. "Aryllead Triacetates: Regioselective Reagents for N-Arylation of Amines". . p. 2095 - 2102. Retrieved 2007/10/02.