N-(2,4,5-Trichlorophenyl)acetamide

Base Information

• Chemical Name: N-(2,4,5-Trichlorophenyl)acetamide
• CAS No.: 23627-24-9
• Molecular Formula: C8H6Cl3NO
• Molecular Weight: 238.501
• Hs Code.: 2924299090
• European Community (EC) Number: 245-793-6
• NSC Number: 80150
• DSSTox Substance ID: DTXSID70178301
• Nikkaji Number: J242.635H
• Wikidata: Q83048688
• Mol file: 23627-24-9.mol

Synonyms:N-(2,4,5-Trichlorophenyl)acetamide;23627-24-9;2,4,5-Trichloroacetanilide;2',4',5'-Trichloroacetanilide;Acetanilide, 2',4',5'-trichloro-;2,4,5-Trichlorophenylacetamide;EINECS 245-793-6;BRN 2939702;3-12-00-01409 (Beilstein Handbook Reference);N-[2,4,5-trichlorophenyl]acetamide;NSC80150;NCIOpen2_004288;SCHEMBL202652;DTXSID70178301;MFCD00018123;NSC 80150;NSC-80150;STL170035;AKOS003412385;N-(2,4,5-Trichlorophenyl)acetamide #;Acetamide, N-(2,4,5-trichlorophenyl)-;CS-0243949;FT-0609789;EN300-270069

Chemical Property of N-(2,4,5-Trichlorophenyl)acetamide

Chemical Property:

• Vapor Pressure: 8.63E-06mmHg at 25°C
• Melting Point: 186-188 °C
• Refractive Index: 1.614
• Boiling Point: 373.969 °C at 760 mmHg
• PKA: 12.65±0.70(Predicted)
• Flash Point: 179.97 °C
• PSA: 29.10000
• Density: 1.506 g/cm³
• LogP: 3.67820
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 236.951497
• Heavy Atom Count: 13
• Complexity: 200

Purity/Quality:

99% ^*data from raw suppliers

2',4',5'-TRICHLOROACETANILIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC(=C(C=C1Cl)Cl)Cl

Technology Process of N-(2,4,5-Trichlorophenyl)acetamide

There total 15 articles about N-(2,4,5-Trichlorophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

acetic anhydride (108-24-7) + 2,4,5-trichloroaniline (636-30-6) → N-(2,4,5-trichlorophenyl)acetamide (23627-24-9)

Guidance literature:

at 20 - 25 ℃;

Reference yield:

acetyl chloride (75-36-5) + 2,4,5-trichloroaniline (636-30-6) → N-(2,4,5-trichlorophenyl)acetamide (23627-24-9)

Guidance literature:

silica gel; In dichloromethane;

Reference yield:

2,5-dichloroacetanilide (2621-62-7) → N-(2,4,5-trichlorophenyl)acetamide (23627-24-9)

Guidance literature:

With acetic acid; Chlorierung;

upstream raw materials:

2,5-dichloroacetanilide

3-Chloroacetanilide

N-(3,4-dichlorophenyl)acetamide

acetic acid-(2,5,N-trichloro-anilide)

Downstream raw materials:

3-nitro-1,2,5-trichloro-4-vinylbenzene

2-bromo-3-nitro-1,4,5-trichlorobenzene

2-nitro-3,4,6-trichlorobenzaldehyde

2,4,5-trichlorobiphenyl

Refernces

• 1、 -. "ENANTIOMERICALLY ENRICHED ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF". Page/Page column 47. . Retrieved 2010/06/13.
• 2、 Stokker, G. E.,Deana, A. A.,deSolms, S. J.,Schultz, E. M.,Smith, R. L.,et al.. "2-(Aminomethyl)phenols, a New Class of Saluretic Agents. 3. Effects of Functional Group Reorientation and Modification". . p. 1063 - 1067. Retrieved 2007/10/02.