N2,N6-bis(1-oxododecyl)-L-lysine

Base Information

• Chemical Name: N2,N6-bis(1-oxododecyl)-L-lysine
• CAS No.: 14379-54-5
• Molecular Formula: C30H58 N2 O4
• Molecular Weight: 510.802
• Mol file: 14379-54-5.mol

Synonyms:Lysine,N2,N6-dilauroyl-, L- (6CI,8CI); Dilauroyl-L-lysine; N2,N6-Dilauryl-L-lysine; Na,Ne-Didodecanoyl-L-lysine

Chemical Property of N2,N6-bis(1-oxododecyl)-L-lysine

Chemical Property:

• Vapor Pressure: 7.55E-22mmHg at 25°C
• Melting Point: 119.5-121 °C
• Boiling Point: 706.5°Cat760mmHg
• PKA: 3.65±0.10(Predicted)
• Flash Point: 381.1°C
• PSA: 95.50000
• Density: 0.962g/cm³
• LogP: 8.46590

Purity/Quality:

99%, ^*data from raw suppliers

Lauroyl-L-Lys(Lauroyl)-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N2,N6-bis(1-oxododecyl)-L-lysine

There total 14 articles about N2,N6-bis(1-oxododecyl)-L-lysine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

n-dodecanoyl chloride (112-16-3) + Nε-lauroyl-L-lysine (52315-75-0) → Nα,Nε-bis(1-oxododecyl)-L-lysine (14379-54-5)

Guidance literature:

With sodium hydroxide; In diethyl ether; at 0 - 20 ℃; for 24h;

DOI:10.1016/j.tet.2008.08.061

Reference yield: 92.0%

N,N'-di-dodecanoyl-lysine methyl ester (340811-37-2) → Nα,Nε-bis(1-oxododecyl)-L-lysine (14379-54-5)

Guidance literature:

With sodium hydroxide; In methanol; for 72h;

DOI:10.1016/j.tet.2007.03.120

Reference yield: 89.7%

Nα-Nε-didodecanoyl-L-lysine benzyl ester (63663-24-1) → Nα,Nε-bis(1-oxododecyl)-L-lysine (14379-54-5)

Guidance literature:

With hydrogen; palladium; In tetrahydrofuran; for 7h;

DOI:10.1039/b818206j

upstream raw materials:

n-dodecanoyl chloride

sodium salt of L-lysine

N^ε-lauroyl-L-lysine

N,N'-di-dodecanoyl-lysine methyl ester

Downstream raw materials:

Nα-Nε-didodecanoyl-N-[2-(benzyloxycarbonyl)ethyl]-L-lysinamide

Refernces

• 1、 Suzuki, Masahiro,Yumoto, Mariko,Kimura, Mutsumi,Shirai, Hirofusa,Hanabusa, Kenji. "New Low-Molecular-Mass Gelators Based on L-Lysine: Amphiphilic Gelators and Water-Soluble Organogelators". . p. 1 - 10. Retrieved 2004.
• 2、 Li, Qiannan,Xu, Baocai,Zhang, Guiju,Zhang, Jieying. "L-Lysine-Based Gelators for the Formation of Oleogels in Four Vegetable Oils". . . Retrieved 2022/02/25.
• 3、 -. "COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF". Paragraph 0773. . Retrieved 2021/06/04.