2-Aminophenazine

Base Information

• Chemical Name: 2-Aminophenazine
• CAS No.: 2876-23-5
• Molecular Formula: C12H9 N3
• Molecular Weight: 195.224
• Hs Code.: 2933990090
• NSC Number: 402912
• UNII: 8BHV6NY38X
• DSSTox Substance ID: DTXSID10182942
• Nikkaji Number: J80.585H
• Wikidata: Q83053667
• Mol file: 2876-23-5.mol

Synonyms:2-Aminophenazine;2-Phenazinamine;phenazin-2-amine;Phenazine, 2-amino-;2876-23-5;CCRIS 3022;2-Phenazinamine (9CI);BRN 0152505;NSC-402912;5-25-11-00338 (Beilstein Handbook Reference);phenazin-2-ylamine;Nc1ccc2nc3ccccc3nc2c1;8BHV6NY38X;SCHEMBL5803173;DTXSID10182942;MFCD00168265;NSC402912;AKOS001012064;NSC 402912;LS-102988;Z56767569

Chemical Property of 2-Aminophenazine

Chemical Property:

• Vapor Pressure: 6.39E-08mmHg at 25°C
• Boiling Point: 439.4°Cat760mmHg
• Flash Point: 249.7°C
• PSA: 51.80000
• Density: 1.333g/cm³
• LogP: 2.94640
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 195.079647300
• Heavy Atom Count: 15
• Complexity: 231

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)N=C3C=CC(=CC3=N2)N

Technology Process of 2-Aminophenazine

There total 4 articles about 2-Aminophenazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

methanol (67-56-1) + 2-azidophenazine (6494-70-8) → phenazin-2-amine (2876-23-5) + 1-amino-2-methoxyphenazine (3224-52-0) + 2-amino-1-chlorophenazine (82100-97-8)

Guidance literature:

With hydrogenchloride; Irradiation;

Reference yield:

Phenazin-mono-N-Oxyd (304-81-4) → phenazin-2-amine (2876-23-5)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄; aqueous HNO₃

2: palladium; methanol / Hydrogenation

With methanol; sulfuric acid; nitric acid; palladium;

DOI:10.1248/cpb1953.2.283

Reference yield:

2,3-diaminephenazine (655-86-7) → Phenazin (92-82-0) + phenazin-2-amine (2876-23-5)

Guidance literature:

With zinc;

upstream raw materials:

2,3-diaminephenazine

methanol

2-azidophenazine

Phenazin-mono-N-Oxyd

Downstream raw materials:

N-(phenazin-2-yl)benzenesulfonamide

N-(phenazin-2-yl)benzamide

N-(phenazin-2-yl)cyclohexanecarboxamide

4-methoxy-N-(phenazin-2-yl)benzamide

Refernces

• 1、 OTOMASU. "Studies on phenazines. VII. Nitration of phenazine and its derivatives.". . p. 283 - 287. Retrieved 2007/10/07.