3-Bromonaphthalen-2-amine

Base Information

• Chemical Name: 3-Bromonaphthalen-2-amine
• CAS No.: 54245-33-9
• Molecular Formula: C10H8 Br N
• Molecular Weight: 222.084
• European Community (EC) Number: 259-043-0
• NSC Number: 97229
• UNII: ZOU7AC2RBE
• DSSTox Substance ID: DTXSID7068928
• Nikkaji Number: J266.835A
• Wikidata: Q81995701
• Mol file: 54245-33-9.mol

Synonyms:3-Bromonaphthalen-2-amine;54245-33-9;2-AMINO-3-BROMONAPHTHALENE;3-Bromo-2-naphthylamine;2-Naphthalenamine, 3-bromo-;ZOU7AC2RBE;3-Bromo-2-naphthalenamine;EINECS 259-043-0;NSC 97229;NSC-97229;NSC97229;UNII-ZOU7AC2RBE;DIMETHYLIMIDOCARBONATE;3-bromo-2-amino naphthalene;C10-H8-Br-N;SCHEMBL6764324;DTXSID7068928;3-BROMO-2-AMINONAPHTHALENE;AKOS015854877;BS-49782;BB 0260165;CS-0188356;FT-0679683;F13558;A929747;AE-562/12222093;2-Naphthalenamine,3-bromo-;3-bromonaphthalen-2-amine

Chemical Property of 3-Bromonaphthalen-2-amine

Chemical Property:

• Vapor Pressure: 6.12E-05mmHg at 25°C
• Melting Point: 168 °C
• Boiling Point: 345.5°Cat760mmHg
• PKA: 2.72±0.10(Predicted)
• Flash Point: 162.8°C
• PSA: 26.02000
• Density: 1.563g/cm³
• LogP: 3.76570
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 220.98401
• Heavy Atom Count: 12
• Complexity: 160

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-3-bromonaphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=C(C(=CC2=C1)N)Br

Technology Process of 3-Bromonaphthalen-2-amine

There total 9 articles about 3-Bromonaphthalen-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-bromo-3-nitronaphthalene (67116-33-0) → 3-bromonaphthalen-2-amine (54245-33-9)

Guidance literature:

With hydrogen; nickel; In ethyl acetate; Ambient temperature;

Reference yield: 71.0%

→ 3-bromonaphthalen-2-amine (54245-33-9)

Guidance literature:

Reference yield:

10-bromo-1,2,3,4,5,6,7,8,13,13,14,14-dodecachloro-1,4,4a,4b,5,8,8a,12b-octahydro-11-nitro-1,4-5,8-dimethanotriphenylene (84605-00-5) → 3-bromonaphthalen-2-amine (54245-33-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / 220 °C / 0.05 - 0.1 Torr

2: 96 percent / H₂ / Raney Ni / ethyl acetate / Ambient temperature

With hydrogen; nickel; In ethyl acetate;

upstream raw materials:

1,3-dibromonaphthalen-2-amine

1,3-dibromo-2-nitro-naphthalene

(3-bromo-[2]naphthyl)-carbamic acid ethyl ester

2-bromo-3-nitronaphthalene

Downstream raw materials:

2,3-dibromonaphthalene

3-bromo-2-naphthol

2-bromo-3-iodonaphthalene

2-bromo-3-nitronaphthalene

Refernces

• 1、 -. "Method of colorimetric analysis of malonic dialdehyde and 4-hydroxy-2-enaldehydes as indexes of lipid peroxidation, kits for carrying out said method, substituted indoles for use in said method and their preparation". . . Retrieved 2008/06/13.