2-phenylcyclopentanol

Base Information

• Chemical Name: 2-phenylcyclopentanol
• CAS No.: 2362-73-4
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.232
• Hs Code.: 2906299090
• Mol file: 2362-73-4.mol

Synonyms:Cyclopentanol,2-phenyl-, cis- (6CI,7CI,8CI); NSC 245131; cis-2-Phenylcyclopentanol

Chemical Property of 2-phenylcyclopentanol

Chemical Property:

• Vapor Pressure: 0.00213mmHg at 25°C
• Boiling Point: 277.8°Cat760mmHg
• Flash Point: 104.2°C
• PSA: 20.23000
• Density: 1.082g/cm³
• LogP: 2.31500

Purity/Quality:

98% ^*data from raw suppliers

2-PHENYLCYCLOPENTAN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-phenylcyclopentanol

There total 19 articles about 2-phenylcyclopentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(+/-)-cis-2-phenylcyclopentyl p-nitrobenzoate → (+/-)-cis-2-phenylcyclopentanol (2362-73-4,38805-76-4,38805-89-9,38805-90-2,38806-01-8,42086-64-6)

Guidance literature:

With sodium hydroxide; In methanol;

DOI:10.1016/j.tetasy.2003.11.013

Reference yield: 86.0%

4,4,5,5-tetramethyl-2-(2-phenylcyclopentyl)-1,3,2-dioxoborolane → (+/-)-cis-2-phenylcyclopentanol (2362-73-4,38805-76-4,38805-89-9,38805-90-2,38806-01-8,42086-64-6)

Guidance literature:

With sodium hydroxide; In water;

DOI:10.1021/ol0262486

Reference yield: 64.0%

2-Phenylcyclopentanone (1198-34-1) → (+/-)-cis-2-phenylcyclopentanol (2362-73-4,38805-76-4,38805-89-9,38805-90-2,38806-01-8,42086-64-6)

Guidance literature:

With L-Selectride; In tetrahydrofuran; 1.) -78 deg C, 6 h, 2.) r.t., overnight;

DOI:10.1021/jo00123a010

upstream raw materials:

(1R,2R)-cis-2-Phenylcyclopentyl (R)-mandelate ester

trans-2-phenylcyclopentan-1-ol

benzoyl chloride

vinyl acetate

Downstream raw materials:

(1R,2R)-2-phenylcyclopentyl acetate

(1R,2R)-(-)-cis-2-Phenylcyclopentanol

(+)-(1S,2S)-2-phenyl-1-cyclopentanol

(1R,2R)-cis-2-Phenylcyclopentyl (R)-mandelate ester

Refernces

• 1、 -. "ERK INHIBITORS". . . Retrieved 2016/07/05.
• 2、 Gonzalez-Sabin, Javier,Gotor, Vicente,Rebolledo, Francisca. "Kinetic resolution of (±)-trans- and (±)-cis-2- phenylcyclopentanamine by CALB-catalyzed aminolysis of esters: The key role of the leaving group". . p. 481 - 488. Retrieved 2007/10/03.