3-METHOXYPROPIONIC ACID

Base Information

• Chemical Name: 3-METHOXYPROPIONIC ACID
• CAS No.: 2544-06-1
• Molecular Formula: C4H8 O3
• Molecular Weight: 104.106
• Hs Code.: 2918990090
• Mol file: 2544-06-1.mol

Synonyms:Propionicacid, 3-methoxy- (7CI,8CI); 3-Methoxypropanoic acid; 3-Methoxypropionic acid; b-Methoxypropionic acid

Chemical Property of 3-METHOXYPROPIONIC ACID

Chemical Property:

• Vapor Pressure: 0.0158mmHg at 25°C
• Refractive Index: n20/D 1.420(lit.)
• Boiling Point: 236.9°Cat760mmHg
• PKA: 4.29±0.10(Predicted)
• Flash Point: 83.9°C
• PSA: 46.53000
• Density: 1.089g/cm³
• LogP: 0.10750
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-MethoxypropanoicAcid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Description: m-PEG1-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Technology Process of 3-METHOXYPROPIONIC ACID

There total 6 articles about 3-METHOXYPROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → 3-Methoxypropionic acid (2544-06-1) + methyl 3-methoxypropionate (3852-09-3)

Guidance literature:

With sodium;

Reference yield:

methyl-(5-phenyl-pent-3-enyl)-ether + acetone (67-64-1) → phenylacetic acid (103-82-2) + 3-Methoxypropionic acid (2544-06-1) + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

Reference yield:

3,5-dimethylphenyl 3-methoxypropionate (133604-77-0) → 3-Methoxypropionic acid (2544-06-1) + 3,5-Dimethylphenol (108-68-9,50356-23-5)

Guidance literature:

With sodium hydroxide; water; In ethanol; at 30 ℃; Rate constant;

DOI:10.1021/ja00009a034

upstream raw materials:

5-ethyl-1-methoxy-hept-4-en-3-one

1-methoxy-5-propyl-oct-4-en-3-one

methanol

acrylic acid methyl ester

Downstream raw materials:

acrylic acid methyl ester

3-methoxypropanoic acid phenyl ester

perfluoropropionic acid methyl ester

methyl 4-oxaperfluoropentanoate

Refernces