2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid

Base Information Edit

Chemical Name:2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid
CAS No.:3588-64-5
Molecular Formula:C17H13NO4
Molecular Weight:295.295
Hs Code.:2925190090
European Community (EC) Number:652-169-0
NSC Number:19760
DSSTox Substance ID:DTXSID10281020
Nikkaji Number:J653.955F
ChEMBL ID:CHEMBL262870
Mol file:3588-64-5.mol

Synonyms:2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid;3588-64-5;38229-08-2;2-(1,3-dioxoisoindol-2-yl)-3-phenylpropanoic acid;NSC19760;2-(1,3-Dioxo-2,3-Dihydro-1H-Isoindol-2-Yl)-3-Phenylpropanoic Acid;MFCD00023056;2-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanoic acid;NSC-19760;N-phthaloyl phenylalanine;ChemDiv2_000002;CBKinase1_000078;CBKinase1_012478;Cambridge id 5108471;Oprea1_238622;Oprea1_554172;CBDivE_002612;CBDivE_003042;MLS000530140;SCHEMBL478614;CHEMBL262870;DTXSID10281020;HMS1369A02;HMS2368H16;N-PHTHALOYL-DL-PHENYLALANINE;2-phthalimido-3-phenylpropionic acid;NSC 19760;STK032198;AKOS000200590;AKOS016039886;LS-05839;NCI60_001645;SMR000135118;EU-0000242;FT-0696199;EN300-16933;alpha-Benzyl-1,3-dioxoisoindoline-2-acetic acid;AE-641/02530020;SR-01000390313;SR-01000390313-1;BRD-A77469519-001-01-4;Z56827158;F1265-0123

Suppliers and Price of 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid
1g
$ 158.00

Matrix Scientific
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid
500mg
$ 126.00

Matrix Scientific
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid
5g
$ 483.00

Crysdot
2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoicacid 95+%
5g
$ 349.00

Chemenu
2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoicacid 95%
5g
$ 329.00

AK Scientific
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoicacid
100mg
$ 605.00

Total 4 raw suppliers

Chemical Property of 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid Edit

Chemical Property:

Vapor Pressure:9.78E-11mmHg at 25°C
Boiling Point:498°Cat760mmHg
Flash Point:255°C
PSA：74.68000
Density:1.406g/cm³
LogP:1.91640
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:295.08445790
Heavy Atom Count:22
Complexity:445

Purity/Quality:

98%min ^*data from raw suppliers

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)O)N2C(=O)C3=CC=CC=C3C2=O

Technology Process of 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid

There total 12 articles about 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 85-44-9
phthalic anhydride

: 673-06-3,25191-15-5,658-69-5,67675-33-6
D-(R)-phenylalanine

: 3588-64-5,5123-55-7,32150-90-6,38229-08-2
(R)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionic acid

Guidance literature:: for 0.05h; microwave irradiation;

Reference yield: 100.0%

: 1242459-38-6
C₂₃H₂₉NO₄Si₂

: 3588-64-5,5123-55-7,32150-90-6,38229-08-2
(R)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionic acid

Guidance literature:: With 2,6-di-tert-butyl-pyridine; 2.6-dimethylphenol; C₃₂H₁₂BF₂₄^(1-)*C₄₄H₃₀N₂O₂P⁽¹⁺⁾; In toluene; at -20 ℃; for 20h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ja105945z