Aminoguanidine hydrochloride

Base Information Edit

Chemical Name:Aminoguanidine hydrochloride
CAS No.:1937-19-5
Molecular Formula:CH6 N4 . Cl H
Molecular Weight:110.546
Hs Code.:29280000
European Community (EC) Number:240-295-5,217-707-7
NSC Number:760398
UNII:A2Z7G2RGAH
DSSTox Substance ID:DTXSID9044405
Wikidata:Q27095586
NCI Thesaurus Code:C76661
ChEMBL ID:CHEMBL1256292
Mol file:1937-19-5.mol

Synonyms:aminoguanidine;aminoguanidine sulfate;hydrazinecarboximidamide;monoaminoguanidine;pimagedine;pimagedine hydrochloride

Suppliers and Price of Aminoguanidine hydrochloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Aminoguanidine Hydrochloride
25g
$ 55.00

TRC
Aminoguanidine Hydrochloride
5g
$ 45.00

TCI Chemical
Aminoguanidine Hydrochloride >98.0%(T)
500g
$ 204.00

TCI Chemical
Aminoguanidine Hydrochloride >98.0%(T)
25g
$ 42.00

TCI Chemical
Aminoguanidine Hydrochloride >98.0%(T)
100g
$ 91.00

SynQuest Laboratories
Aminoguanadine hydrochloride 98%
100 g
$ 135.00

SynQuest Laboratories
Aminoguanadine hydrochloride 98%
500 g
$ 173.00

Sigma-Aldrich
Aminoguanidine hydrochloride ≥98%
25g
$ 45.10

Sigma-Aldrich
Aminoguanidine hydrochloride ≥98%
100g
$ 135.00

CSNpharm
AminoguanidineHCl
100mg
$ 54.00

Total 115 raw suppliers

Chemical Property of Aminoguanidine hydrochloride Edit

Chemical Property:

Appearance/Colour:White to off-white solid.
Vapor Pressure:0.0116mmHg at 25°C
Melting Point:162-166 °C(lit.)
Boiling Point:261.4 °C at 760 mmHg
Flash Point:111.9 °C
PSA：87.92000
Density:g/cm³
LogP:1.03640
Storage Temp.:Store at RT
Solubility.:Completely soluble in water
Water Solubility.:506.7g/L at 20℃
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:110.0359239
Heavy Atom Count:6
Complexity:41.6

Purity/Quality:

99% ^*data from raw suppliers

Aminoguanidine Hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(=NN)(N)N.Cl
Uses Aminoguanidine Hydrochloride is used in the synthetic preparation of highly selective and potent G-protein-coupled receptor kinase 2 (GRK2) inhibitor for potential treatment of heart failure. antitussive a-Glucosidase inhibitor; hydroxyethyl derivative of 1-deoxynojirimycin Aminoguanidine hydrochloride may be employed as nitric oxide synthase (NOS) inhibitor to investigate its effect on the reduction of alveolar bone loss in ligature induced periodontitis in rats. It may be used in the synthesis of 5-guanylhydrazone derivatives, having antibacterial activity against antibacterial activity against both Escherichia coli and Staphylococcus aureus.
Description Aminoguanidine is equipotent to L-NMMA and L-NNA as an inhibitor of iNOS. The IC50 values for inhibition of mouse iNOS and rat nNOS are 5.4 and 160 μM, respectively. Aminoguanidine also inhibits induction of iNOS protein expression by endotoxin in rat macrophages.

Technology Process of Aminoguanidine hydrochloride

There total 6 articles about Aminoguanidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%