2-(2-Chlorophenyl)succinic acid

Base Information

• Chemical Name: 2-(2-Chlorophenyl)succinic acid
• CAS No.: 6954-40-1
• Molecular Formula: C10H9ClO4
• Molecular Weight: 228.6291
• Hs Code.: 2917399090
• NSC Number: 37764
• DSSTox Substance ID: DTXSID90284579
• Mol file: 6954-40-1.mol

Synonyms:2-(2-Chlorophenyl)succinic acid;6954-40-1;2-(2-CHLORO-PHENYL)-SUCCINIC ACID;2-(2-chlorophenyl)butanedioic acid;MFCD06658406;o-Chlorophenylsuccinic acid;3-(chlorophenyl)-succinic acid;SCHEMBL2456546;DTXSID90284579;JKZMBINIIFRDHY-UHFFFAOYSA-N;NSC37764;2-(2-Chlorophenyl)succinic acid #;AB1347;NSC-37764;AKOS022308961;SB38359;SY239847;EN300-704757;A836539;24300-08-1

Chemical Property of 2-(2-Chlorophenyl)succinic acid

Chemical Property:

• Vapor Pressure: 4.41E-05mmHg at 25°C
• Refractive Index: 1.59
• Boiling Point: 336.4 °C at 760 mmHg
• Flash Point: 157.3 °C
• PSA: 74.60000
• Density: 1.454 g/cm³
• LogP: 1.98290
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 228.0189365
• Heavy Atom Count: 15
• Complexity: 254

Purity/Quality:

98% ^*data from raw suppliers

2-(2-Chloro-phenyl)-succinicacid 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(CC(=O)O)C(=O)O)Cl

Technology Process of 2-(2-Chlorophenyl)succinic acid

There total 5 articles about 2-(2-Chlorophenyl)succinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-(2-chlorophenyl)-2-cyanoacrylate (24393-43-9,140241-90-3,14561-93-4) + sodium cyanide (143-33-9,25596-52-5) → 3-(2-Chlorophenyl)succinic acid (6954-40-1)

Guidance literature:

With ethanol; Erhitzen des Reaktionsprodukts mit konz. wss. Salzsaeure;

DOI:10.1021/ja01866a053

Reference yield:

3-(2-Chlorophenyl)succinic acid (6954-40-1) → D-(2-chloro-phenyl)-succinic acid (6954-40-1)

Guidance literature:

With strychnidin-10-one;

DOI:10.1021/ja01866a053

Reference yield:

3-(2-Chlorophenyl)succinic acid (6954-40-1) → L-(2-chloro-phenyl)-succinic acid (6954-40-1)

Guidance literature:

With strychnidin-10-one;

DOI:10.1021/ja01866a053

upstream raw materials:

ethyl 3-(2-chlorophenyl)-2-cyanoacrylate

sodium cyanide

Downstream raw materials:

2-cyclohexylsuccinic acid

(+/-)-(2-chloro-phenyl)-succinic acid-anhydride

3-(2-Chloro-phenyl)-1-[1,3,4]thiadiazol-2-yl-pyrrolidine-2,5-dione

3-(2-Chloro-phenyl)-1-cyclohexyl-pyrrolidine-2,5-dione