CYCLOHEXYLSUCCINIC ACID

Base Information

• Chemical Name: CYCLOHEXYLSUCCINIC ACID
• CAS No.: 1489-63-0
• Molecular Formula: C10H16 O4
• Molecular Weight: 200.235
• Hs Code.: 2917209090
• Mol file: 1489-63-0.mol

Synonyms:Butanedioicacid, cyclohexyl- (9CI); Cyclohexanesuccinic acid (7CI,8CI); Succinic acid,cyclohexyl- (4CI); 2-Cyclohexylsuccinic acid

Chemical Property of CYCLOHEXYLSUCCINIC ACID

Chemical Property:

• Melting Point: 145-147 °C(lit.)
• Boiling Point: 334.7±15.0 °C(Predicted)
• PKA: 4.55±0.23(Predicted)
• PSA: 74.60000
• Density: 1.218±0.06 g/cm3(Predicted)
• LogP: 1.74220

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cyclohexylsuccinic acid 96% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CYCLOHEXYLSUCCINIC ACID

There total 17 articles about CYCLOHEXYLSUCCINIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-Cyclohexylbutandisaeure-anhydrid (5962-96-9) → 2-cyclohexylsuccinic acid (1489-63-0)

Guidance literature:

With potassium hydroxide; water; In methanol; for 3h; Heating;

DOI:10.1021/ja00005a051

Reference yield:

dimethyl cis-but-2-ene-1,4-dioate (624-48-6) + cyclohexylmagnesium bromide (931-50-0) → 2-cyclohexylsuccinic acid (1489-63-0)

Guidance literature:

With diethyl ether; Behandeln des nach der Hydrolyse (wss. Salzsaeure) erhaltenen Reaktionsprodukts mit methanol. Kalilauge;

DOI:10.1007/s12122-002-1031-5

Reference yield:

→ 2-cyclohexylsuccinic acid (1489-63-0)

Guidance literature:

With barium dihydroxide; anschliessend hydrieren an Platin in Essigsaeure bei 120grad/70 at;

DOI:10.1021/ja01640a017

upstream raw materials:

2-(Cyclohex-1-enyl)-bernsteinsaeure

2-Cyclohexylbutandisaeure-diethylester

2-phenylsuccinic acid

3-(2-Chlorophenyl)succinic acid

Downstream raw materials:

3-cyclohexyl-pyrrolidine-2,5-dione

(S)-(+)-2-cyclohexylbutanedioic acid

(2R)-2-cyclohexylsuccinic acid

2-Cyclohexylbutandisaeure-anhydrid

Refernces

• 1、 Porter, Ned A.,Scott, Daniel M.,Rosenstein, Ian J.,Giese, Bernd,Veit, Andreas,Zeitz, Heinz Georg. "Stereoselective intermolecular radical additions to amide-substituted alkenes". . p. 1791 - 1799. Retrieved 2007/10/02.