(4-Chlorophenyl)azanium;chloride

Base Information

• Chemical Name: (4-Chlorophenyl)azanium;chloride
• CAS No.: 20265-96-7
• Molecular Formula: C6H6ClN.ClH
• Molecular Weight: 164.034
• Hs Code.: 2921440000
• Mol file: 20265-96-7.mol

Synonyms:(4-chlorophenyl)azanium;chloride

Chemical Property of (4-Chlorophenyl)azanium;chloride

Chemical Property:

• Appearance/Colour: White to off-white crystaline solid
• Melting Point: 230 °C (subl.)
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 232 °C at 760 mmHg
• Flash Point: 89.5 °C
• PSA: 26.02000
• Density: 1.3807 (rough estimate)
• LogP: 3.30540
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Water Solubility.: within almost transparency
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 162.9955546
• Heavy Atom Count: 9
• Complexity: 69.5

Purity/Quality:

98% ^*data from raw suppliers

p-ChloroanilineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 23/24/25-33-40-50/53-22
• Safety Statements: 28-36/37-45-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1[NH3+])Cl.[Cl-]

Technology Process of (4-Chlorophenyl)azanium;chloride

There total 31 articles about (4-Chlorophenyl)azanium;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.9%

2-chloro-N-(4-chlorophenyl)acetamide (3289-75-6) → p-chloroaniline hydrochloride (20265-96-7)

Guidance literature:

With thionyl chloride; In methanol; for 1.2h; Reflux;

DOI:10.1007/s11164-011-0327-6

Reference yield: 96.0%

C21H16ClNO3 → 1,3-diphenyl-propane-1,2,3-trione (643-75-4) + p-chloroaniline hydrochloride (20265-96-7)

Guidance literature:

With hydrogenchloride; In dichloromethane; water; at 20 ℃;

DOI:10.1016/j.tet.2016.03.093

Reference yield: 93.1%

N-(4-chlorophenyl)acetamide (539-03-7) → p-chloroaniline hydrochloride (20265-96-7)

Guidance literature:

With thionyl chloride; In methanol; for 2.5h; Reflux;

DOI:10.1007/s11164-011-0327-6

upstream raw materials:

(4-Chloro-phenyl)-(6-{[(E)-4-chloro-phenylimino]-methyl}-2-methoxy-8,9-dihydro-7H-benzocyclohepten-5-yl)-amine; hydrochloride

4-chloro-aniline

1-chloro-2,4-dinitro-benzene

1-(4-Chloro-phenyl)-3-(3-phenyl-3-thioxo-thiopropionyl)-urea

Downstream raw materials:

1-(4-chlorophenyl)guanidine

1-(4'-chlorophenyl)-2-phenyl-4,6-diamino-1,2-dihydro-1,3,5-triazine hydrochloride

(4-chlorophenyl)(oxiranylmethyl)amine

(E)-azulen-1-yl-(4-chloro-phenyl)-diazene

Refernces

• 1、 -. "Synthesis method of 4-chlorobenzene cyanoguanidine". Paragraph 0011-0017. . Retrieved 2021/02/10.
• 2、 -. "p-chloroaniline hydrochloride preparation method". Paragraph 0109-0114; 0119; 0124; 0132; 0140-0141; 0145; 0149. . Retrieved 2019/11/29.