Glycylsarcosine zwitterion

Base Information

• Chemical Name: Glycylsarcosine zwitterion
• CAS No.: 29816-01-1
• Molecular Formula: C5H10 N2 O3
• Molecular Weight: 146.146
• Hs Code.: 2924199090
• Mol file: 29816-01-1.mol

Synonyms:[3H]GlySar;[3H]-GlySar;tritiated glycylsarcosine;Gly-Sar zwitterion;glycylsarcosine zwitterion;glycyl-sarcosine zwitterion;D0Q3VU;N-glycylsarcosine zwitterion;glycyl-N-methylglycine zwitterion;CHEBI:155838;N-glycyl-N-methylglycine zwitterion;[(azaniumylacetyl)(methyl)amino]acetate

Chemical Property of Glycylsarcosine zwitterion

Chemical Property:

• Vapor Pressure: 2.6E-05mmHg at 25°C
• Melting Point: 198-202oC (dec.)
• Boiling Point: 333.5°Cat760mmHg
• PKA: pK1:2.98(＋1);pK2:8.55(0) (25°C,μ=0.1)
• Flash Point: 155.5°C
• PSA: 83.63000
• Density: 1.284g/cm³
• LogP: -0.81160
• Storage Temp.: −20°C
• XLogP3: -3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 146.06914219
• Heavy Atom Count: 10
• Complexity: 140

Purity/Quality:

98%,99%, ^*data from raw suppliers

Gly-Sar-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN(CC(=O)[O-])C(=O)C[NH3+]

Technology Process of Glycylsarcosine zwitterion

There total 4 articles about Glycylsarcosine zwitterion which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl N-(2-chloroacetyl)glycine (65332-01-6) → Glycylsarcosine (29816-01-1)

Guidance literature:

With ammonia; bie Zimmertemperatur;

Reference yield:

C35H54N14O10 → Glycylsarcosine (29816-01-1) + C30H46N12O8

Guidance literature:

In aq. phosphate buffer; Kinetics;

Reference yield:

Z-Gly-Sar-OH (7801-91-4) → Glycylsarcosine (29816-01-1)

Guidance literature:

With methanol; palladium; acetic acid; Hydrogenolyse;

upstream raw materials:

methyl N-(2-chloroacetyl)glycine

Z-Gly-Sar-OH

Downstream raw materials:

1-methylpiperazin-2,5-dione

N-Cbz-D-Ser[N-Me-Boc-Val]-(S)-β-L-triisopropylsilyloxy-Pip-Gly-Sar allyl ester

C₄₅H₇₃N₅O₁₂Si

N-Cbz-D-Ser[N-Me-Boc-Val]-(S)-β-L-hydroxy-Pip-Gly-Sar allyl ester

Refernces

• 1、 Jiang, Hui,Newcombe, Nicole,Sutton, Philip,Lin, Qing Hui,Muellbacher, Arno,Waring, Paul. "Synthesis and Activity of New Epipolythiopiperazine-2,5-dione Compounds. I". . p. 1743 - 1754. Retrieved 2007/10/02.