3-phospho-D-glyceroyl dihydrogen phosphate

Base Information

• Chemical Name: 3-phospho-D-glyceroyl dihydrogen phosphate
• CAS No.: 38168-82-0
• Molecular Formula: C3H8O10P2
• Molecular Weight: 266.038
• DSSTox Substance ID: DTXSID101305707
• Nikkaji Number: J40.060B
• Wikipedia: 1,3-Bisphosphoglyceric_acid
• Wikidata: Q27098334
• Metabolomics Workbench ID: 50340
• Mol file: 38168-82-0.mol

Synonyms:1,3-biphosphoglycerate;1,3-biphosphoglyceric acid;1,3-bisphosphoglycerate;1,3-diphosphoglycerate;3-phosphoglyceroyl phosphate;glycerate 1,3-biphosphate

Chemical Property of 3-phospho-D-glyceroyl dihydrogen phosphate

Chemical Property:

• Vapor Pressure: 5.32E-19mmHg at 25°C
• Boiling Point: 638.7°Cat760mmHg
• Flash Point: 340°C
• PSA: 190.44000
• Density: 2.143g/cm³
• LogP: -1.90750
• XLogP3: -3.9
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 6
• Exact Mass: 265.95927044
• Heavy Atom Count: 15
• Complexity: 311

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(C(C(=O)OP(=O)(O)O)O)OP(=O)(O)O
• Isomeric SMILES: C([C@H](C(=O)OP(=O)(O)O)O)OP(=O)(O)O

Technology Process of 3-phospho-D-glyceroyl dihydrogen phosphate

There total 25 articles about 3-phospho-D-glyceroyl dihydrogen phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phosphoglyceric acid (820-11-1,3443-58-1,73358-94-8,111614-09-6) + ATP (56-65-5,896506-78-8) → glyceric acid 1,3-biphosphate (38168-82-0,1981-49-3) + adenosine 5'-diphosphate (58-64-0,905904-58-7)

Guidance literature:

With human phosphoglycerate kinase; magnesium chloride; diothiothreitol; In various solvent(s); at 25 ℃; pH=7.5; Enzyme kinetics;

DOI:10.1016/j.bcp.2004.06.012

Reference yield:

DL-glyceraldehyde 3-phosphate (142-10-9,591-57-1,20283-52-7,591-59-3) → glyceric acid 1,3-biphosphate (38168-82-0,1981-49-3)

Guidance literature:

With dipotassium hydrogenphosphate; NAD; glyceraldehyde-3-phosphate dehydrogenase; In various solvent(s); at 25 ℃; for 0.2h; pH=7.5;

DOI:10.1016/j.bcp.2004.06.012

Reference yield:

D-glyceraldehyde-3-phosphate (591-57-1) → glyceric acid 1,3-biphosphate (38168-82-0,1981-49-3)

Guidance literature:

With aldehyde dehydrogenase from Bacillus stearothermophilus; C₂₂H₂₈N₇O₁₆P₃^(4-); In aq. buffer; at 30 ℃; pH=8; Reagent/catalyst; Catalytic behavior; Enzymatic reaction;

DOI:10.1002/anie.202017027

upstream raw materials:

D-glyceraldehyde-3-phosphate

D-(-)-3-phosphoglyceric acid

L-ATP

3-phosphoglyceric acid

Downstream raw materials:

D-(-)-3-phosphoglyceric acid

3-phosphoglyceric acid

ATP

Refernces

• 1、 Schormann, Norbert,Campos, Juan,Motamed, Rachael,Hayden, Katherine L.,Gould, Joseph R.,Green, Todd J.,Senkovich, Olga,Banerjee, Surajit,Ulett, Glen C.,Chattopadhyay, Debasish. "Chlamydia trachomatis glyceraldehyde 3-phosphate dehydrogenase: Enzyme kinetics, high-resolution crystal structure, and plasminogen binding". . p. 2446 - 2458. Retrieved 2020.
• 2、 Dai, Zhihui,Li, Zhenxi,Lu, Yuxiao,Sheng, Enze,Tan, Yuting,Xiao, Yue. "Oxidase-mimicking activity of ultrathin MnO2 nanosheets in a colorimetric assay of chlorothalonil in food samples". . . Retrieved 2020/07/02.