N-Formyl-L-tyrosine

Base Information

• Chemical Name: N-Formyl-L-tyrosine
• CAS No.: 13200-86-7
• Molecular Formula: C10H11 N O4
• Molecular Weight: 209.202
• Hs Code.: 2924299090
• ChEMBL ID: CHEMBL1275735
• DSSTox Substance ID: DTXSID201315501
• Metabolomics Workbench ID: 57465
• Nikkaji Number: J208.511I
• Wikidata: Q27122136
• Mol file: 13200-86-7.mol

Synonyms:N-Formyl-L-tyrosine;13200-86-7;L-Tyrosine, N-formyl-;N-Formyl tyrosine;(S)-2-Formamido-3-(4-hydroxyphenyl)propanoic acid;(2S)-3-(4-hydroxyphenyl)-2-formamidopropanoic acid;CHEBI:50603;(2S)-2-(formylamino)-3-(4-hydroxyphenyl)propanoic acid;N-Formyl-Tyrosine;L-Tyrosine,N-formyl-;(2S)-2-formamido-3-(4-hydroxyphenyl)propanoic acid;SCHEMBL2703294;CHEMBL1275735;DTXSID201315501;N-Formyl-4-hydroxyphenylalanine #;MFCD00021031;AKOS010365907;N-Formyl-L-tyrosine (For-L-Tyr-OH);HY-W142001;AS-57533;CS-0201787;F0135;T71712;A806349;Q27122136

Chemical Property of N-Formyl-L-tyrosine

Chemical Property:

• Vapor Pressure: 3.21E-12mmHg at 25°C
• Melting Point: 165 °C
• Refractive Index: 83 ° (C=2.6, EtOH)
• Boiling Point: 533.7°Cat760mmHg
• Flash Point: 276.6°C
• PSA: 86.63000
• Density: 1.351g/cm³
• LogP: 1.16070
• Storage Temp.: −20°C
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 209.06880783
• Heavy Atom Count: 15
• Complexity: 224

Purity/Quality:

99% ^*data from raw suppliers

N-Formyl-L-tyrosine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CC=C1CC(C(=O)O)NC=O)O
• Isomeric SMILES: C1=CC(=CC=C1C[C@@H](C(=O)O)NC=O)O

Technology Process of N-Formyl-L-tyrosine

There total 3 articles about N-Formyl-L-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-tyrosine (60-18-4,18875-48-4,25619-78-7,30704-25-7) → N-formyl-L-tyrosine (13200-86-7)

Guidance literature:

Reference yield:

formic acid (64-18-6) + L-tyrosine (60-18-4,18875-48-4,25619-78-7,30704-25-7) → N-formyl-L-tyrosine (13200-86-7)

Guidance literature:

With acetic anhydride;

DOI:10.1246/bcsj.25.265

Reference yield:

L-tyrosine (60-18-4,18875-48-4,25619-78-7,30704-25-7) + formyl acetic anhydride (2258-42-6) → N-formyl-L-tyrosine (13200-86-7)

Guidance literature:

In formic acid;

DOI:10.1246/bcsj.38.244

upstream raw materials:

formic acid

L-tyrosine

formyl acetic anhydride

Downstream raw materials:

O-ethyl-L-tyrosine ; hydrochloride

N-L-tyrosyl-L-leucine benzyl ester; hydrochloride

O-Methyltyrosine

N-Formyl-O-methyl-L-tyrosin-methylester

Refernces

• 1、 MURAMATSU,MURAKAMI,YONEDA,HAGITANI. "THE FORMYLATION OF AMINO ACIDS WITH ACETIC FORMIC ANHYDRIDE.". . p. 244 - 246. Retrieved 2007/10/05.