Cyclohexanamine;cyclohexylcarbamodithioic acid

Base Information

• Chemical Name: Cyclohexanamine;cyclohexylcarbamodithioic acid
• CAS No.: 18879-86-2
• Molecular Formula: C13H26N2S2
• Molecular Weight: 274.495
• Mol file: 18879-86-2.mol

Synonyms:SCHEMBL11174371

Chemical Property of Cyclohexanamine;cyclohexylcarbamodithioic acid

Chemical Property:

• Vapor Pressure: 0.028mmHg at 25°C
• Boiling Point: 245.9°C at 760 mmHg
• Flash Point: 102.5°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 274.15374118
• Heavy Atom Count: 17
• Complexity: 165

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)N.C1CCC(CC1)NC(=S)S

Technology Process of Cyclohexanamine;cyclohexylcarbamodithioic acid

There total 9 articles about Cyclohexanamine;cyclohexylcarbamodithioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

carbon disulfide (75-15-0,12122-00-8) + cyclohexylamine (108-91-8,157973-60-9) → cyclohexylaminodithiocarboxylic acid, cyclohexylammonium salt (18879-86-2)

Guidance literature:

In water; at 20 ℃; for 2h;

DOI:10.3762/bjoc.13.20

Reference yield: 78.0%

Thiram (137-26-8,93196-73-7) + cyclohexylamine (108-91-8,157973-60-9) → N-cyclohexyl-N',N'-dimethylthiourea (24070-58-4) + N-cyclohexyl-S-(N,N-dimethylthiocarbamoyl)thiohydroxylamine (52243-24-0) + cyclohexylaminodithiocarboxylic acid, cyclohexylammonium salt (18879-86-2) + cyclohexylammonium N,N-dimethyldithiocarbamate

Guidance literature:

at 20 ℃; for 3h; Further Variations:; Temperatures; Solvents; Product distribution;

DOI:10.1007/BF02498275

Reference yield:

4-methoxy-aniline (104-94-9) → cyclohexylaminodithiocarboxylic acid, cyclohexylammonium salt (18879-86-2)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; hydrochloric acid; acetic acid / 40 - 50 °C / Hydrogenation

With hydrogenchloride; acetic acid; platinum;

upstream raw materials:

carbon disulfide

cyclohexylamine

Thiram

4-amino-phenol

Downstream raw materials:

1,3-dicyclohexylthiourea

isothiocyanatocyclohexane

N-cyclohexyl-N',N'-dimethylthiourea

N-cyclohexylbenzo[d]oxazol-2-amine

Refernces

• 1、 Basu Baul, Tushar S.,Addepalli, Maheswara Rao,Duthie, Andrew,Guedes da Silva, M. Fátima C.. "Reconnaissance of the reactions of carbamodithiolate salts with dialkyltin dichloride". . . Retrieved 2021.
• 2、 Fathalla, Walid,Ali, Ibrahim A. I.,Pazdera, Pavel. "A novel method for heterocyclic amide-thioamide transformations". . p. 174 - 181. Retrieved 2017/02/15.