DI-TERT-BUTYLPHENYLPHOSPHINE

Base Information

• Chemical Name: DI-TERT-BUTYLPHENYLPHOSPHINE
• CAS No.: 32673-25-9
• Molecular Formula: C14H23P
• Molecular Weight: 222.31
• Hs Code.: 2931499090
• Mol file: 32673-25-9.mol

Synonyms:Di(tert-butyl)(phenyl)phosphine;Di-tert-butylphenylphosphine;Di-tert-butyl(phenyl)phosphane;

Chemical Property of DI-TERT-BUTYLPHENYLPHOSPHINE

Chemical Property:

• Vapor Pressure: 0.00457mmHg at 25°C
• Refractive Index: n20/D 1.5382
• Boiling Point: 286.4 °C at 760 mmHg
• Flash Point: 132 °C
• PSA: 13.59000
• Density: 0.933 g/mL at 25 °C
• LogP: 4.39080
• Sensitive.: air sensitive

Purity/Quality:

98%, ^*data from raw suppliers

Di-tert-butylphenylphosphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F，Xi
• Hazard Codes: F,Xi
• Statements: 17-36/37/38
• Safety Statements: 6-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Di-tert-butylphenylphosphine is used as a catalyst in the cross-coupling of secondary organotrifluoroborates with aryl chlorides and bromides.

Technology Process of DI-TERT-BUTYLPHENYLPHOSPHINE

There total 15 articles about DI-TERT-BUTYLPHENYLPHOSPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.7%

bromobenzene (108-86-1,52753-63-6) + di(tert-butyl)chlorophosphine (13716-10-4) → di(tertbutyl)phenylphosphine (32673-25-9)

Guidance literature:

bromobenzene; With magnesium; In tetrahydrofuran; for 2h; Inert atmosphere; Reflux;

di(tert-butyl)chlorophosphine; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 3h; Reflux; Inert atmosphere;

Reference yield: 89.0%

di(tert-butyl)chlorophosphine (13716-10-4) + phenylmagnesium chloride (100-59-4) → di(tertbutyl)phenylphosphine (32673-25-9)

Guidance literature:

copper(I) bromide; In tetrahydrofuran; at 25 - 40 ℃; for 4h;

Reference yield: 88.5%

di(tert-butyl)chlorophosphine (13716-10-4) + phenylmagnesium bromide (100-58-3) → di(tertbutyl)phenylphosphine (32673-25-9)

Guidance literature:

copper(I) bromide; at 25 - 40 ℃; for 4h; Quantum yield;

upstream raw materials:

bromobenzene

di(tert-butyl)chlorophosphine

tert.-butyl lithium

Dichlorophenylphosphine

Downstream raw materials:

3,5-bis(trifluoromethyl)cinnamonitrile

trans-{di-tert-butylphenylphosphine}2-rhodium(I)Cl(CO)

trans-carbonylchlorobis(phenyldi-t-butylphosphine)iridium(I)

Pt3(μCO)3(P-tert.-Bu2Ph)3

Refernces

• 1、 Rodriguez, Jessica,Culver, Damien B.,Conley, Matthew P.. "Generation of Phosphonium Sites on Sulfated Zirconium Oxide: Relationship to Br?nsted Acid Strength of Surface -OH Sites". . p. 1484 - 1488. Retrieved 2019/01/25.
• 2、 Li, Yuehui,Das, Shoubhik,Zhou, Shaolin,Junge, Kathrin,Beller, Matthias. "General and selective copper-catalyzed reduction of tertiary and secondary phosphine oxides: Convenient synthesis of phosphines". supporting information; experimental part. p. 9727 - 9732. Retrieved 2012/07/14.