3,3'-(1,1,3,3-Tetramethyldisiloxane-1,3-diyl)dipropanol

Base Information

• Chemical Name: 3,3'-(1,1,3,3-Tetramethyldisiloxane-1,3-diyl)dipropanol
• CAS No.: 18001-97-3
• Molecular Formula: C10H26 O3 Si2
• Molecular Weight: 250.486
• Hs Code.: 2934999090
• European Community (EC) Number: 241-916-2
• DSSTox Substance ID: DTXSID60170899
• Nikkaji Number: J260.825A
• Wikidata: Q72446063
• Mol file: 18001-97-3.mol

Synonyms:18001-97-3;3,3'-(1,1,3,3-Tetramethyldisiloxane-1,3-diyl)bis(propan-1-ol);3,3'-(1,1,3,3-Tetramethyldisiloxane-1,3-diyl)dipropanol;3-[[3-hydroxypropyl(dimethyl)silyl]oxy-dimethylsilyl]propan-1-ol;1,3-bis(hydroxypropyl)tetramethyldisiloxane;1,3-bis(3-hydroxypropyl)tetramethyldisiloxane;EINECS 241-916-2;1,3-BIS(3-HYDROXYPROPYL)-1,1,3,3-TETRAMETHYLDISILOXANE;C10H26O3Si2;SCHEMBL1054599;DTXSID60170899;C10-H26-O3-Si2;AMY42195;MFCD00054854;CS-0448572;I10448;A851811;1,3-BIS(HYDROXYPROPYL)TETRAMETHYL-DISILOXANE;1,3-BIS(HYDROXYPROPYL)TETRAMETHYLDISILOXANE?;3,3'-[Oxybis(dimethylsilanediyl)]bis(propane-1-ol);1-Propanol, 3,3'-(1,1,3,3-tetramethyl-1,3-disiloxanediyl)bis-

Chemical Property of 3,3'-(1,1,3,3-Tetramethyldisiloxane-1,3-diyl)dipropanol

Chemical Property:

• Vapor Pressure: 0.0299mmHg at 25°C
• Melting Point: <0°C
• Refractive Index: 1.4472 [25°C]
• Boiling Point: 75 °C
• PKA: 14.89±0.10(Predicted)
• Flash Point: 84.8°C
• PSA: 49.69000
• Density: 0.94g/cm³
• LogP: 2.17800
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 250.14204776
• Heavy Atom Count: 15
• Complexity: 154

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,3'-(1,1,3,3-Tetramethyldisiloxane-1,3-diyl)bis(propan-1-ol) 95+% ^*data from reagent suppliers

Safty Information:

• Statements: 10-36/37/38
• Safety Statements: 16-26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(CCCO)O[Si](C)(C)CCCO

Technology Process of 3,3'-(1,1,3,3-Tetramethyldisiloxane-1,3-diyl)dipropanol

There total 13 articles about 3,3'-(1,1,3,3-Tetramethyldisiloxane-1,3-diyl)dipropanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,3-bis(3-formyloxypropyl)tetramethyldisiloxane (40171-30-0) → 4,4,6,6-tetramethyl-5-oxa-4,6-disila-nonane-1,9-diol (18001-97-3)

Guidance literature:

With formate dehydrogenase; water; for 17h; Enzymatic reaction;

DOI:10.1039/c1ob06064c

Reference yield: 95.8%

1,3-bis(3-trimethylsilyloxypropyl)tetramethyldisiloxane (18547-30-3) → 4,4,6,6-tetramethyl-5-oxa-4,6-disila-nonane-1,9-diol (18001-97-3)

Guidance literature:

With water; toluene-4-sulfonic acid; at 90 ℃; for 1h; Time; Temperature; Microwave irradiation;

DOI:10.14233/ajchem.2016.19413

Reference yield: 93.0%

1,1,3,3-Tetramethyldisiloxane (3277-26-7) + allyl alcohol (107-18-6) → 4,4,6,6-tetramethyl-5-oxa-4,6-disila-nonane-1,9-diol (18001-97-3)

Guidance literature:

With platinum⁽⁰⁾-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex; In toluene; at 20 ℃; for 4h; Reflux;

DOI:10.1021/bm100295z

upstream raw materials:

2,2-dimethyl-1-oxa-2-silacyclopentane

3-[1,1,3,3-Tetramethyl-3-(3-oxo-propyl)-disiloxanyl]-propionaldehyde

allyloxydimethylsilane

1,3-bis(3-trimethylsilyloxypropyl)tetramethyldisiloxane

Downstream raw materials:

1,3-bis<3-(2-methylpropenoyloxy)propyl>tetramethyldisiloxane

1,3-bis<3-(2-propenoyloxy)propyl>tetramethyldisiloxane

4,4,6,6-tetramethyl-5-oxa-4,6-disila-nonanedioic acid

(3-chloropropyl)dimethylchlorosilane

Refernces

• 1、 Cheng, Xitao,Li, Wenhong,Zhang, Cunshe,Huang, Fangfang,Wang, Qianjin,Zhou, Kui. "Microwave-assisted synthesis of 1,3-bis(3-hydroxypropyl)-1,1,3,3-tetramethyldisiloxane". . p. 567 - 571. Retrieved 2016.
• 2、 Froehlich, Peter,Albert, Kristin,Bertau, Martin. "Formate dehydrogenase - A biocatalyst with novel applications in organic chemistry". . p. 7941 - 7950. Retrieved 2011.
• 3、 -. "A dog (d) for the preparation of hexamethyl disilane". Paragraph 0046; 0077; 0078; 0083. . Retrieved 2018/05/30.
• 4、 Frampton, Mark B.,Séguin, Jacqueline P.,Marquardt, Drew,Harroun, Thad A.,Zelisko, Paul M.. "Synthesis of polyesters containing disiloxane subunits: Structural characterization, kinetics, and an examination of the thermal tolerance of Novozym-435". . p. 149 - 155. Retrieved 2013/01/15.