Chloro(3-chloropropyl)dimethylsilane

Base Information

• Chemical Name: Chloro(3-chloropropyl)dimethylsilane
• CAS No.: 10605-40-0
• Molecular Formula: C5H12Cl2Si
• Molecular Weight: 171.142
• Hs Code.: 29319090
• European Community (EC) Number: 234-234-1
• UNII: FT64JR6F9M
• DSSTox Substance ID: DTXSID1065138
• Nikkaji Number: J227.030G
• Wikidata: Q72458042
• Mol file: 10605-40-0.mol

Synonyms:10605-40-0;Chloro(3-chloropropyl)dimethylsilane;3-CHLOROPROPYLDIMETHYLCHLOROSILANE;chloro-(3-chloropropyl)-dimethylsilane;Silane, chloro(3-chloropropyl)dimethyl-;Chloropropyldimethylchlorosilane;C5H12Cl2Si;(3-Chloropropyl)dimethylchlorosilane;FT64JR6F9M;EINECS 234-234-1;EC 234-234-1;CPCDMSi;(3-Chloropropyl)chlorodimethylsilane;3-(chlorodimethylsilyl)propyl chloride;Me2SiClCH2CH2CH2Cl;UNII-FT64JR6F9M;SCHEMBL159716;DTXSID1065138;3-chloropropylchlorodimethylsilane;3-chloropropyl dimethylchlorosilane;3-chloropropylchloro dimethylsilane;3-chloropropylchlorodimethyl-silane;3-chloropropyl-chlorodimethyl-silane;AMY42212;3-Chloropropyl Dimethyl Chlorosilane;3-chloro-n-propyldimethylchlorosilane;MFCD00042612;AKOS016010280;Chloro(3-chloropropyl)dimethylsilane #;1-Dimethyl(3-chloropropyl)silyl chloride;AS-49505;DIMETHYL(3-CHLOROPROPYL)CHLOROSILANE;C3426;FT-0693138;(3-CHLOROPROPYL)DIMETHYLSILYL CHLORIDE;chloranyl-(3-chloranylpropyl)-dimethyl-silane;EN300-107807;I11057;A801664;J-001537;Chloro(3-chloropropyl)dimethylsilane, technical, >=95% (GC)

Chemical Property of Chloro(3-chloropropyl)dimethylsilane

Chemical Property:

• Vapor Pressure: 1.96mmHg at 25°C
• Refractive Index: n20/D 1.450
• Boiling Point: 170.3 °C at 760 mmHg
• Flash Point: 61 °C
• PSA: 0.00000
• Density: 1.009 g/cm³
• LogP: 3.05920
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 170.0085323
• Heavy Atom Count: 8
• Complexity: 63.4

Purity/Quality:

99.9% ^*data from raw suppliers

Chloro(3-chloropropyl)dimethylsilane >96.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-37
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](C)(CCCCl)Cl
• Uses: Chloro(3-chloropropyl)dimethylsilane can be used as:A starting material to prepare misonidazole-based 18F-radiolabeled organosilicon compounds as positron emission tomography (PET) ligands for medical imaging applications.An intermediate in the synthesis of block copolymers.

Technology Process of Chloro(3-chloropropyl)dimethylsilane

There total 21 articles about Chloro(3-chloropropyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

dimethylmonochlorosilane (1066-35-9) + 3-chloroprop-1-ene (107-05-1) → (3-chloropropyl)dimethylchlorosilane (10605-40-0)

Guidance literature:

3-chloroprop-1-ene; With bis(1,5-cyclooctadiene)diiridium(I) dichloride; cyclo-octa-1,5-diene; at 40 ℃; for 0.166667h; Reflux; Inert atmosphere; Schlenk technique; Glovebox;

dimethylmonochlorosilane; at 40 ℃; for 0.166667h; Concentration; Catalytic behavior; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1016/j.jcat.2015.09.003

Reference yield: 95.2%

trimethylene oxide (503-30-0) + dimethylsilicon dichloride (75-78-5,30107-43-8) → (3-chloropropyl)dimethylchlorosilane (10605-40-0)

Guidance literature:

for 2.5h; Heating;

DOI:10.1021/jo00349a034

Reference yield: 95.0%

1,5-cis,cis-cyclooctadiene (1552-12-1,111-78-4) + di-μ-chlorobis[(cycloocta-1c, 5c-diene)iridium + dimethylmonochlorosilane (1066-35-9) + 3-chloroprop-1-ene (107-05-1) → (3-chloropropyl)dimethylchlorosilane (10605-40-0)

Guidance literature:

upstream raw materials:

dichloro(3-chloropropyl)methylsilane

methylmagnesium chloride

4,4,6,6-tetramethyl-5-oxa-4,6-disila-nonane-1,9-diol

dimethylmonochlorosilane

Downstream raw materials:

chloropropyl(dimethyl)ethoxysilane

dimethyl(3-chloropropyl)silane

Allylchlorodimethylsilane

(3-aminopropyl)methoxydimethylsilane

Refernces

• 1、 Riener, Korbinian,Meister, Teresa K.,Gigler, Peter,Herrmann, Wolfgang A.,Kühn, Fritz E.. "Mechanistic insights into the iridium-catalyzed hydrosilylation of allyl compounds". . p. 203 - 209. Retrieved 2015.
• 2、 -. "PROCESS FOR SYNTHESIS OF ORGANOSILICON COMPOUNDS FROM HALOSILANES". Paragraph 0160-0161. . Retrieved 2022/02/09.
• 3、 Naganawa, Yuki,Nakajima, Yumiko,Sakamoto, Kei. "A General and Selective Synthesis of Methylmonochlorosilanes from Di-, Tri-, and Tetrachlorosilanes". supporting information. p. 601 - 606. Retrieved 2021/01/13.