panaxoside A progenin

Base Information

• Chemical Name: panaxoside A progenin
• CAS No.: 53963-43-2
• Molecular Formula: C36H62O9
• Molecular Weight: 638.883
• Wikidata: Q105331648
• Mol file: 53963-43-2.mol

Synonyms:MFCD06410947;panaxoside A progenin;SCHEMBL21297623;SY068854;(3|A,6|A,12|A)-3,6,12-trihydroxydammar-24-en-20-yl |A-D-glucopyranoside

Chemical Property of panaxoside A progenin

Chemical Property:

• Vapor Pressure: 3.65E-26mmHg at 25°C
• Boiling Point: 752.9°Cat760mmHg
• PKA: 12.94±0.70(Predicted)
• Flash Point: 409.1°C
• PSA: 160.07000
• Density: 1.23g/cm³
• LogP: 3.29560
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly )
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 7
• Exact Mass: 638.43938355
• Heavy Atom Count: 45
• Complexity: 1110

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ginsenoside F1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)O)C)O)C)OC5C(C(C(C(O5)CO)O)O)O)C
• Uses: Ginsenoside F1 is a bioactive metabolite of the ginsenoside component of Panax ginseng with the ability to inhibit human cytochrome P450 enzymes. This has application in anti-cancer therapeutics as well as protective liver effects.

Technology Process of panaxoside A progenin

There total 3 articles about panaxoside A progenin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ginsenoside-Rg1 (22427-39-0) → β-D-glucose (492-61-5) + ginsenoside F1 (53963-43-2)

Guidance literature:

With Penicillium decumbens naringinase; enzymatic hydrolysis;

DOI:10.1055/s-2003-38476

Reference yield:

ginsenoside Re (52286-59-6) → β-D-glucose (492-61-5) + L-rhamnose (6014-42-2) + ginsenoside F1 (53963-43-2)

Guidance literature:

With Penicillium decumbens naringinase; enzymatic hydrolysis;

DOI:10.1055/s-2003-38476

Reference yield:

notoginsenoside R1 → ginsenoside-Rg1 (22427-39-0) + ginsenoside F1 (53963-43-2) + 20(S)-protopanaxatriol (32773-56-1)

Guidance literature:

With human intestinal bacteria; In dimethyl sulfoxide; at 37 ℃; Microbiological reaction; In air;

DOI:10.1021/jf1005885

upstream raw materials:

ginsenoside-Rg₁

ginsenoside Re

Refernces

• 1、 Ko, Sung-Ryong,Choi, Kang-Ju,Uchida, Kei,Suzuki, Yukio. "Enzymatic preparation of ginsenosides Rg2, Rh1, and F1 from protopanaxatriol-type ginseng saponin mixture". . p. 285 - 286. Retrieved 2007/10/03.