Ginsenoside Re

Base Information

• Chemical Name: Ginsenoside Re
• CAS No.: 52286-59-6
• Molecular Formula: C48H82O18
• Molecular Weight: 947.168
• Hs Code.: 29389090
• European Community (EC) Number: 257-814-6
• UNII: 46F3R0BL3I
• DSSTox Substance ID: DTXSID801317298
• Nikkaji Number: J38.851C
• Wikidata: Q27105064
• Metabolomics Workbench ID: 155112
• ChEMBL ID: CHEMBL510095
• Mol file: 52286-59-6.mol

Synonyms:ginsenoside Re;ginsenoside-Re

Chemical Property of Ginsenoside Re

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 201～203℃
• Refractive Index: 1.61
• Boiling Point: 1011.8 °C at 760 mmHg
• PKA: 12.85±0.70(Predicted)
• Flash Point: 565.7 °C
• PSA: 298.14000
• Density: 1.38 g/cm³
• LogP: -0.02840
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 12
• Hydrogen Bond Acceptor Count: 18
• Rotatable Bond Count: 12
• Exact Mass: 946.55011576
• Heavy Atom Count: 66
• Complexity: 1700

Purity/Quality:

Ginsenoside Re ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(C(C(C(O1)OC2C(C(C(OC2OC3CC4(C(CC(C5C4(CCC5C(C)(CCC=C(C)C)OC6C(C(C(C(O6)CO)O)O)O)C)O)C7(C3C(C(CC7)O)(C)C)C)C)CO)O)O)O)O)O
• Isomeric SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2O[C@H]3C[C@@]4([C@H](C[C@H]([C@H]5[C@]4(CC[C@@H]5[C@](C)(CCC=C(C)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)O)[C@@]7([C@@H]3C([C@H](CC7)O)(C)C)C)C)CO)O)O)O)O)O
• Recent ClinicalTrials: A Clinical Trial of Ginseng in Diabetes
• Uses: Ginsenoside Re is an extract from ginger, responsible for some of the pharmacological functions. It displays cardiac contractility, anti-ischemic and anti-arrythmic activities.

Technology Process of Ginsenoside Re

There total 1 articles about Ginsenoside Re which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pseudo-ginsenoside-RS1 (106533-58-8) → ginsenoside-Re (52286-59-6)

Guidance literature:

With potassium hydroxide; In methanol; at 80 ℃; for 0.0833333h;

DOI:10.1248/cpb.34.4368

Reference yield:

ginsenoside Re (52286-59-6) → 20(S)-ginsenoside Rg2 (52286-74-5,80952-72-3)

Guidance literature:

With β-glucosidase; at 85 ℃; for 1h; pH=5.5; Enzymatic reaction;

DOI:10.1007/s10600-017-2025-0

Reference yield:

ginsenoside Re (52286-59-6) → ginsenoside F4 + 3β,12β,20,25-tetrahydroxy-dammarane (80952-74-5) + 3β,12β,20,25-tetrahydroxy-dammarane (80952-74-5) + ginsenoside 25-OH-Rg6 + ginsenoside 25-OH-F4 + 20(S)-ginsenoside Rg2 (52286-74-5,80952-72-3) + 6α-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl]-5R,9R,13R-dammarane-20(21),24(25)-diene-3β,12β-diol + 3β,12β,20-trihydroxy-dammar-24-ene

Guidance literature:

With dodecatungstophosphoric acid hexahydrate; water; at 80 ℃;

DOI:10.1039/c6nj01702a

upstream raw materials:

pseudo-ginsenoside-RS₁

Downstream raw materials:

β-D-glucose

L-rhamnose

ginsenoside Rh₁

ginsenoside F₁

Refernces