3-CHLOROPROPIONIC ACID PHENYL ESTER

Base Information

• Chemical Name: 3-CHLOROPROPIONIC ACID PHENYL ESTER
• CAS No.: 24552-27-0
• Molecular Formula: C9H9 Cl O2
• Molecular Weight: 184.622
• Hs Code.: 2915900090
• Mol file: 24552-27-0.mol

Synonyms:Propionicacid, 3-chloro-, phenyl ester (8CI); 3-Chloropropionic acid, phenyl ester; NSC64457; Phenyl 3-chloropropionate; Phenyl w-chloropropionate

Chemical Property of 3-CHLOROPROPIONIC ACID PHENYL ESTER

Chemical Property:

• Vapor Pressure: 0.0067mmHg at 25°C
• Refractive Index: 1.5160-1.5200
• Boiling Point: 270.8°Cat760mmHg
• Flash Point: 131°C
• PSA: 26.30000
• Density: 1.191g/cm³
• LogP: 2.22090
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

Phenyl3-Chloropropanoate ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-CHLOROPROPIONIC ACID PHENYL ESTER

There total 6 articles about 3-CHLOROPROPIONIC ACID PHENYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acryloyl chloride (814-68-6,25189-84-8) + phenol (108-95-2,27073-41-2) → phenyl acrylate (937-41-7) + 3-chloropropionic acid phenyl ester (24552-27-0)

Guidance literature:

With aluminium trichloride; In neat (no solvent); Yield given. Yields of byproduct given. Title compound not separated from byproducts; 1.) cooled by tap water, 16 h, 2.) 80 deg C, 4 h;

DOI:10.1139/v87-035

Reference yield:

acrylic acid (79-10-7) + phenol (108-95-2,27073-41-2) → phenyl acrylate (937-41-7) + 3-chloropropionic acid phenyl ester (24552-27-0)

Guidance literature:

With phosphorus pentachloride; In neat (no solvent); Yield given. Yields of byproduct given. Title compound not separated from byproducts; 1.) 110-120 deg C, 1 h, 2.) room temp., 2.5 h then 90 deg C, 3 h;

DOI:10.1139/v87-035

Reference yield:

4-chloro-2-butanone (6322-49-2) + phenol (108-95-2,27073-41-2) → 3-chloropropionic acid phenyl ester (24552-27-0)

Guidance literature:

With trifluoroacetic anhydride;

DOI:10.1021/ja00708a044

upstream raw materials:

acryloyl chloride

phenol

4-chloro-2-butanone

chloropropionic acid

Downstream raw materials:

8-methoxy-1,2,3,4-tetrahydroisoquinoline

8-methoxy-3,4-dihydroisoquinolin-1(2H)-one

phenyl 3-phenylpropanoate

1-(4-hydroxyphenyl)-3'-oxopropyl-β-D-glucopyranose

Refernces