3-Dodecanol

Base Information

• Chemical Name: 3-Dodecanol
• CAS No.: 10203-30-2
• Molecular Formula: C12H26O
• Molecular Weight: 186.338
• Hs Code.: 2905199090
• NSC Number: 158523
• DSSTox Substance ID: DTXSID30871200
• Nikkaji Number: J112.112J
• Mol file: 10203-30-2.mol

Synonyms:3-Dodecanol;dodecan-3-ol;10203-30-2;(R)-dodecan-3-ol;581107-05-3;dodecanol-3;3-hydroxydodecane;NSC158523;SCHEMBL378929;DTXSID30871200;CHEBI:195617;AKOS011018658;NSC 158523;NSC-158523;FT-0719225

Chemical Property of 3-Dodecanol

Chemical Property:

• Vapor Pressure: 0.00476mmHg at 25°C
• Melting Point: 25 °C
• Refractive Index: 1.439
• Boiling Point: 245.5 °C at 760 mmHg
• PKA: 15.28±0.20(Predicted)
• Flash Point: 100.1 °C
• PSA: 20.23000
• Density: 0.829 g/cm³
• LogP: 3.89800
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 9
• Exact Mass: 186.198365449
• Heavy Atom Count: 13
• Complexity: 91.1

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Alcohols and Polyols, Other
• Canonical SMILES: CCCCCCCCCC(CC)O

Technology Process of 3-Dodecanol

There total 8 articles about 3-Dodecanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

Methyl decanoate (110-42-9) + ethylmagnesium bromide (925-90-6) → dodecan-3-ol (10203-30-2)

Guidance literature:

With zinc(II) tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1080/00397910008087324

Reference yield: 64.0%

caprinaldehyde (112-31-2) + ethylmagnesium bromide (925-90-6) → dodecan-3-ol (10203-30-2)

Guidance literature:

In tetrahydrofuran; at -78 - 25 ℃; for 2h;

Reference yield:

dodecane (112-40-3) → lauric acid (143-07-7) + dodecan-2-one (6175-49-1) + Dodecanal (112-54-9) + dodecan-3-ol (10203-30-2) + rac-2-dodecanol (10203-28-8) + 1-dodecyl alcohol (112-53-8)

Guidance literature:

With oxygen; Mn-ALPO-18; at 99.9 ℃; for 24h; under 11250.9 Torr; Product distribution; other manganese-containing molecular sieve catalysts;

DOI:10.1039/a803984d

upstream raw materials:

caprinaldehyde

ethylmagnesium bromide

3-dodecanone

ethyloxirane

Downstream raw materials:

3-dodecanone

Refernces

• 1、 Braga, Antonio L.,Paixao, Marcio W.,Luedtke, Diogo S.,Silveira, Claudio C.,Rodrigues, Oscar E. D.. "Synthesis of new chiral aliphatic amino diselenides and their application as catalysts for the enantioselective addition of diethylzinc to aldehydes". . p. 2635 - 2638. Retrieved 2003.
• 2、 -. "IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES". Page/Page column 164. . Retrieved 2020/11/04.