Adenosine 5-(tetrahydrogen triphosphate), tetrasodium salt

Base Information

• Chemical Name: Adenosine 5-(tetrahydrogen triphosphate), tetrasodium salt
• CAS No.: 606-67-7
• Molecular Formula: C₁₀H₁₄N₅O₁₃P₃*2Na
• Molecular Weight: 551.148
• Mol file: 606-67-7.mol

Synonyms:

Chemical Property of Adenosine 5-(tetrahydrogen triphosphate), tetrasodium salt

Chemical Property:

• Boiling Point: 951.4°Cat760mmHg
• Flash Point: 529.2°C
• Density: g/cm³

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Adenosine 5-(tetrahydrogen triphosphate), tetrasodium salt

There total 13 articles about Adenosine 5-(tetrahydrogen triphosphate), tetrasodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

adenosine 5′-phosphoropiperidate triethylammonium salt (1577254-51-3) → adenosine 5'-triphosphate (606-67-7,987-65-5,4691-96-7,15237-44-2,20978-32-9,71997-34-7,71997-37-0,71997-53-0,71997-56-3)

Guidance literature:

adenosine 5′-phosphoropiperidate triethylammonium salt; With 4,5-dicyano-1H-imidazole; tris(tetra-n-butylammonium) hydrogen pyrophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 6h; Inert atmosphere;

With sodium acetate; In ethanol; water; Further stages; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.02.031

Reference yield: 58.0%

C54H54N21O42P9(12-) → adenosine 5'-triphosphate (606-67-7,987-65-5,4691-96-7,15237-44-2,20978-32-9,71997-34-7,71997-37-0,71997-53-0,71997-56-3)

Guidance literature:

C₅₄H₅₄N₂₁O₄₂P₉^(12-); With ammonium hydroxide; at 50 ℃; Sealed tube;

In methanol; water; at 50 ℃; for 5h; Sealed tube;

Sealed tube;

DOI:10.1002/ejoc.202100544

Reference yield:

adenosine 5'-trimetaphosphate (53355-60-5) → adenosine 5'-triphosphate (606-67-7,987-65-5,4691-96-7,15237-44-2,20978-32-9,71997-34-7,71997-37-0,71997-53-0,71997-56-3) + adenosine-5′-diphosphate trisodium salt (1172-42-5,2092-65-1,16178-48-6,20398-34-9,71997-33-6,71997-36-9,71997-52-9,71997-55-2)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1039/c39910001276

upstream raw materials:

adenosine 5'-trimetaphosphate

C₁₀H₁₂Cl₂N₅O₅P

adenosine

adenosine (5'-phosphoro-1-piperidinide)

Downstream raw materials:

adenosine 5'-diphosphate

Refernces

• 1、 Appy, Lucie,Peyrottes, Suzanne,Roy, Béatrice. "Supported Synthesis of Adenosine Nucleotides and Derivatives on a Benzene-Centered Tripodal Soluble Support". . . Retrieved 2021/06/23.
• 2、 Sun, Qi,Gong, Shanshan,Sun, Jian,Liu, Si,Xiao, Qiang,Pu, Shouzhi. "A P(V)-N activation strategy for the synthesis of nucleoside polyphosphates". . p. 8417 - 8426. Retrieved 2013/09/24.