4-CHLOROANILIDOPHOSPHORYL DICHLORIDE

Base Information

• Chemical Name: 4-CHLOROANILIDOPHOSPHORYL DICHLORIDE
• CAS No.: 6971-73-9
• Molecular Formula: C6H5Cl3NOP
• Molecular Weight: 244.445
• Mol file: 6971-73-9.mol

Synonyms:phosphoramidic dichloride, N-(4-chlorophenyl)-;4-Chloroanilidophosphoryl Dichloride;

Chemical Property of 4-CHLOROANILIDOPHOSPHORYL DICHLORIDE

Chemical Property:

• Vapor Pressure: 0.000493mmHg at 25°C
• Melting Point: 105-107 °C
• Refractive Index: 1.613
• Boiling Point: 313.6 °C at 760 mmHg
• PKA: -4.25±0.50(Predicted)
• Flash Point: 143.4 °C
• PSA: 38.91000
• Density: 1.616 g/cm³
• LogP: 4.41060

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLOROANILIDOPHOSPHORYL DICHLORIDE

There total 3 articles about 4-CHLOROANILIDOPHOSPHORYL DICHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

p-chloroaniline hydrochloride (20265-96-7) → N-p-chlorophenylphosphoramidic dichloride (6971-73-9)

Guidance literature:

With trichlorophosphate; for 3h; Heating;

DOI:10.1016/0040-4020(82)80240-8

Reference yield:

4-chloro-aniline (106-47-8) → N-p-chlorophenylphosphoramidic dichloride (6971-73-9)

Guidance literature:

With trichlorophosphate;

Reference yield:

→ N-p-chlorophenylphosphoramidic dichloride (6971-73-9)

Guidance literature:

p-Chloranilin, 1) PCl5, Bzl., 2) konz. Ameisensaeure unter Kuehlung;

upstream raw materials:

4-chloro-aniline

p-chloroaniline hydrochloride

Downstream raw materials:

diethyl (4-chlorophenyl)phosphoramidate

(4-chloro-phenyl)-diamidophosphoric acid

(5,5-Bis-chloromethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-(4-chloro-phenyl)-amine

2-(4-chloroanilino)-1,3,2-diazaphosphorinane-2-oxide

Refernces