N-(2-Aminoethyl)glycine

Base Information

• Chemical Name: N-(2-Aminoethyl)glycine
• CAS No.: 24123-14-6
• Molecular Formula: C4H10N2O2
• Molecular Weight: 118.136
• Hs Code.: 2922499990
• European Community (EC) Number: 607-325-2
• DSSTox Substance ID: DTXSID50178844
• Nikkaji Number: J21.911H
• Wikidata: Q72436774
• Metabolomics Workbench ID: 160012
• Mol file: 24123-14-6.mol

Synonyms:2-((2-ammonioethyl)amino)acetate dihydrate;2-((2-ammonioethyl)ammonio)acetate iodide;N-(2-aminoethyl)glycine;N-(2-aminoethyl)glycine dihydrate;N-(2-aminoethyl)glycine monosodium salt;N-2-aminoethylglycine

Chemical Property of N-(2-Aminoethyl)glycine

Chemical Property:

• Appearance/Colour: White Solid
• Vapor Pressure: 0.000524mmHg at 25°C
• Melting Point: 140-143 °C
• Refractive Index: 1.487
• Boiling Point: 290.272 °C at 760 mmHg
• PKA: 2.21±0.10(Predicted)
• Flash Point: 129.352 °C
• PSA: 75.35000
• Density: 1.161 g/cm³
• LogP: -0.28950
• Storage Temp.: -15°C
• Solubility.: Methanol (Slightly, Sonicated), Water (Slightly)
• Water Solubility.: very faint turbidity
• XLogP3: -3.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 118.074227566
• Heavy Atom Count: 8
• Complexity: 74.4

Purity/Quality:

98% ^*data from raw suppliers

N-(2-Aminoethyl)glycine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38-36
• Safety Statements: 24/25-36-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: other linear non-peptide (BMAA)
• Canonical SMILES: C(CNCC(=O)O)N

Technology Process of N-(2-Aminoethyl)glycine

There total 8 articles about N-(2-Aminoethyl)glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

ethylenediamine (107-15-3,85404-18-8) + chloroacetic acid (79-11-8) → N-(2-Aminoethyl)glycine (24123-14-6)

Guidance literature:

for 22h;

DOI:10.1002/bkcs.11340

Reference yield: 72.0%

ethylenediamine (107-15-3,85404-18-8) → N-(2-Aminoethyl)glycine (24123-14-6)

Guidance literature:

at 25 ℃; for 48h;

DOI:10.1021/jo00047a022

Reference yield: 55.0%

ethylenediamine (107-15-3,85404-18-8) + Glyoxilic acid (298-12-4) → N-(2-Aminoethyl)glycine (24123-14-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; water; under 225.02 Torr; Ambient temperature;

DOI:10.1016/0040-4020(95)00766-2

upstream raw materials:

formaldehyd

sodium cyanide

ethylenediamine

2-Ketopiperazine

Downstream raw materials:

N-[2-(4,6-dichloro-2-nitro-benzenesulfonylamino)-ethyl]-glycine ethyl ester

N-benzyloxycarbonyl-N-(2-t.butoxycarbonylaminoethyl)glycine

1-carboxymethyl-2-iminoimidazolidine

C₂₁H₂₈N₆O₆S

Refernces

• 1、 Lee, Yeong Deok,Yoon, Kyung Sun,Chun, Keun Ho. "Synthesis of peptide nucleic acid dimer containing modified cytosine". . p. 10 - 11. Retrieved 2017/12/28.
• 2、 -. "SYNTHESIS OF CYCLOCREATINE AND ANALOGS THEREOF". Paragraph 0047; 0048. . Retrieved 2016/09/26.