3,5-DICHLOROBENZOIC ACID METHYL ESTER

Base Information

• Chemical Name: 3,5-DICHLOROBENZOIC ACID METHYL ESTER
• CAS No.: 2905-67-1
• Molecular Formula: C8H6Cl2O2
• Molecular Weight: 205.04
• Hs Code.: 2916399090
• Mol file: 2905-67-1.mol

Synonyms:3,5-Dichlorobenzoicacid methyl ester;Methyl 3,5-dichlorobenzoate;

Chemical Property of 3,5-DICHLOROBENZOIC ACID METHYL ESTER

Chemical Property:

• Vapor Pressure: 0.00575mmHg at 25°C
• Melting Point: 56 °C
• Refractive Index: 1.545
• Boiling Point: 273.4 °C at 760 mmHg
• Flash Point: 118.1 °C
• PSA: 26.30000
• Density: 1.355 g/cm³
• LogP: 2.78000
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99.9% ^*data from raw suppliers

METHYL 3,5-DICHLOROBENZOATE ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3,5-DICHLOROBENZOIC ACID METHYL ESTER

There total 11 articles about 3,5-DICHLOROBENZOIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

3,5-dichlorobenzoic acid (51-36-5) + trimethylsulphonium hydroxide (17287-03-5) → methyl 3,5-dichlorobenzoate (2905-67-1)

Guidance literature:

In ethyl acetate; at 20 ℃; for 2h;

DOI:10.1016/S0045-6535(97)00205-1

Reference yield: 78.0%

methanol (67-56-1) + 3,5-dichlorobenzaldehyde (10203-08-4) → methyl 3,5-dichlorobenzoate (2905-67-1)

Guidance literature:

With Oxone; indium(lll) trifluoromethanesulfonate; for 2.5h; Reflux;

DOI:10.1248/cpb.c13-00072

Reference yield: 63.0%

methanol (67-56-1) + 3,5-dichlorobenzoic acid (51-36-5) → methyl 3,5-dichlorobenzoate (2905-67-1)

Guidance literature:

Acidic conditions;

upstream raw materials:

diazomethane

3,5-dichlorobenzoic acid

methanol

3,5-dichlorobenzoyl chloride

Downstream raw materials:

3,5-dichloro-N-methylbenzamide

1-(3,5-dichlorophenyl)-2,2,2-trifluoro-1-trimethylsilyloxy-1-methoxyethane

methyl 3-chlorobenzoate

C₁₃H₁₆BClO₄

Refernces

• 1、 -. "METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND, METHOD FOR PRODUCTION OF 2-PROPEN-1-ONE COMPOUND, AND METHOD FOR PRODUCTION OF ISOXAZOLINE COMPOUND". Page/Page column 73; 86. . Retrieved 2010/04/25.
• 2、 -. "1,3-BIS(SUBSTITUTED PHENYL)-3-HYDROXYPROPAN-1-ONE OR 2-PROPEN-1-ONE COMPOUND, AND SALT THEREOF". Page/Page column 62. . Retrieved 2008/12/07.