3-Vinylphenol

Base Information

• Chemical Name: 3-Vinylphenol
• CAS No.: 620-18-8
• Molecular Formula: C8H8O
• Molecular Weight: 120.151
• Hs Code.: 2907199090
• European Community (EC) Number: 826-731-2
• DSSTox Substance ID: DTXSID00211033
• Nikkaji Number: J227.717D
• Wikidata: Q83085885
• Mol file: 620-18-8.mol

Synonyms:3-Vinylphenol;620-18-8;3-ethenylphenol;m-vinylphenol;Phenol, 3-ethenyl-;3-Hydroxystyrene;3-vinyl-phenol;3-Hydroxy-styrol;SCHEMBL92327;DTXSID00211033;YNGIFMKMDRDNBQ-UHFFFAOYSA-N;MFCD19300724;AKOS017258516;LS-09126;CS-0134614;FT-0675826;EN300-42607;D93526;A937092

Chemical Property of 3-Vinylphenol

Chemical Property:

• Vapor Pressure: 0.0427mmHg at 25°C
• Melting Point: 1°C
• Refractive Index: 1.5804
• Boiling Point: 230.8°Cat760mmHg
• PKA: 9.79±0.10(Predicted)
• Flash Point: 103.5°C
• PSA: 20.23000
• Density: 1.055g/cm³
• LogP: 2.03520
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 120.057514874
• Heavy Atom Count: 9
• Complexity: 98.7

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC1=CC(=CC=C1)O

Technology Process of 3-Vinylphenol

There total 30 articles about 3-Vinylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Methyltriphenylphosphonium bromide (1779-49-3) + meta-hydroxybenzaldehyde (100-83-4) → 3-hydroxystyrene (620-18-8,24979-69-9)

Guidance literature:

Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; for 1h;

meta-hydroxybenzaldehyde; In tetrahydrofuran; for 16h; Inert atmosphere;

Reference yield: 99.0%

3-hydroxy phenylacetylene (10401-11-3) → 3-hydroxystyrene (620-18-8,24979-69-9)

Guidance literature:

With formic acid; iron(II) tetrafluoroborate hexahydrate; tris(2-diphenylphosphinoethyl)phosphine; In tetrahydrofuran; at 40 ℃; for 5h; Inert atmosphere;

DOI:10.1039/c2cc31091k

Reference yield: 91.0%

tert-butyldimethyl-(3-vinylphenoxy)silane (149274-04-4) → 3-hydroxystyrene (620-18-8,24979-69-9)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.tetlet.2008.01.135

upstream raw materials:

methyl magnesium iodide

3-benzoyloxybenzaldehyde

3-ethylphenol

3-(1-hydroxyethyl)phenol

Downstream raw materials:

2-(3-vinyl-phenoxy)-tetrahydro-pyran

(E)-3',5'-dimethoxy-4'-fluoro-3-hydroxystilbene

(E)-2',3,5'-trihydroxystilbene

(E)-2',4'-dimethoxy-3-hydroxystilbene

Refernces

• 1、 -. "MODIFIED MONOMER, MODIFIED POLYMER COMPRISING THE SAME AND METHOD FOR PREPARING THEM". Paragraph 0171-0174. . Retrieved 2021/05/18.
• 2、 Zheng, Yuqin,Tan, Taixing,Wang, Cheng. "Seed-mediated Growth of Alloyed Ag-Pd Shells toward Alkyne Semi-hydrogenation Reactions under Mild Conditions?". . p. 3071 - 3078. Retrieved 2021/09/13.