N-furfurylformamide

Base Information

• Chemical Name: N-furfurylformamide
• CAS No.: 72693-10-8
• Molecular Formula: C6H7 N O2
• Molecular Weight: 125.127
• Mol file: 72693-10-8.mol

Synonyms:N-Furfurylformamide

Chemical Property of N-furfurylformamide

Chemical Property:

• Vapor Pressure: 0.000642mmHg at 25°C
• Boiling Point: 309.4°C at 760 mmHg
• Flash Point: 140.9°C
• Density: 1.125g/cm³

Purity/Quality:

99% ^*data from raw suppliers

N-[(furan-2-yl)methyl]formamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-furfurylformamide

There total 15 articles about N-furfurylformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

furan-2-ylmethanamine (617-89-0) + formic acid ethyl ester (109-94-4) → N-(furan-2-ylmethyl)formamide (72693-10-8)

Guidance literature:

With Novozyme 435 CALB; In tetrahydrofuran; at 20 ℃; Green chemistry; Enzymatic reaction;

DOI:10.1039/c6cc07679c

Reference yield: 98.0%

furfural (98-01-1) + formamide (77287-34-4,77287-35-5,60100-09-6) → N-(furan-2-ylmethyl)formamide (72693-10-8)

Guidance literature:

With formic acid; at 180 ℃; for 0.05h; Microwave irradiation;

DOI:10.1021/acs.orglett.5b00759

Reference yield: 95.0%

formic acid (64-18-6) + furan-2-ylmethanamine (617-89-0) → N-(furan-2-ylmethyl)formamide (72693-10-8)

Guidance literature:

With 4-methyl-morpholine; dmap; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine; In dichloromethane; at 35 ℃; for 0.1h; microwave irradiation;

DOI:10.1055/s-2004-834788

upstream raw materials:

formic acid

furan-2-ylmethanamine

N-formylimidazole

formic acid ethyl ester

Downstream raw materials:

furan-2-ylmethanamine

Furfurylisocyanid<(2-Furylmethyl)isocyanid>

Refernces

• 1、 Dan, Demin,Chen, Fubo,Zhao, Whenshu,Yu, Han,Han, Sheng,Wei, Yongge. "Chromium-catalysed efficient: N -formylation of amines with a recyclable polyoxometalate-supported green catalyst". supporting information. p. 90 - 94. Retrieved 2021/01/11.
• 2、 Wu, Zhikang,Zhai, Yongyan,Zhao, Wenshu,Wei, Zheyu,Yu, Han,Han, Sheng,Wei, Yongge. "An efficient way for the: N -formylation of amines by inorganic-ligand supported iron catalysis". supporting information. p. 737 - 741. Retrieved 2020/02/25.