BENZENEHEXACARBOXYLIC ACID HEXAMETHYL ESTER

Base Information

• Chemical Name: BENZENEHEXACARBOXYLIC ACID HEXAMETHYL ESTER
• CAS No.: 6237-59-8
• Molecular Formula: C18H18 O12
• Molecular Weight: 426.334
• Hs Code.: 2917399090
• Mol file: 6237-59-8.mol

Synonyms:Benzenehexacarboxylicacid, hexamethyl ester (7CI,8CI,9CI); Mellitic acid, hexamethyl ester (6CI);Hexa(carbomethoxy)benzene; Hexakis(carbomethoxy)benzene;Hexakis(methoxycarbonyl)benzene; Hexamethyl benzenehexacarboxylate; Hexamethylmellitate; NSC 70056

Chemical Property of BENZENEHEXACARBOXYLIC ACID HEXAMETHYL ESTER

Chemical Property:

• Melting Point: 190 °C
• Refractive Index: 1.7500 (estimate)
• Boiling Point: 501.82°C (rough estimate)
• Flash Point: 174.7oC
• PSA: 157.80000
• Density: 1.4578 (rough estimate)
• LogP: 0.40620

Purity/Quality:

98%,99%, ^*data from raw suppliers

HexamethylBenzene-1,2,3,4,5,6-hexacarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BENZENEHEXACARBOXYLIC ACID HEXAMETHYL ESTER

There total 105 articles about BENZENEHEXACARBOXYLIC ACID HEXAMETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

dimethyl acetylenedicarboxylate (762-42-5) → hexamethyl benzenehexacarboxylate (6237-59-8)

Guidance literature:

[Rh(CO)Cl(1,2-bis(diphenylphosphino)ethane)]; In tetrahydrofuran-d8; at 65 ℃; for 1h;

DOI:10.1071/CH99154

Reference yield: 100.0%

hydrogen cyanide (74-90-8) + dimethyl acetylenedicarboxylate (762-42-5) → hexamethyl benzenehexacarboxylate (6237-59-8)

Guidance literature:

With triphenyl phosphite; tetrakis(triphenylphosphite)nickel⁽⁰⁾; zinc(II) chloride; In toluene; at 60 ℃; for 0.5h;

Reference yield: 98.0%

dimethyl acetylenedicarboxylate (762-42-5) + hex-1-yne (693-02-7) → hexamethyl benzenehexacarboxylate (6237-59-8) + tetramethyl 5-(n-butyl)-1,2,3,4-benzenetetracarboxylate (128408-43-5)

Guidance literature:

With 1,2-bis-(diphenylphosphino)ethane; bis(1,5-cyclooctadiene)diiridium(I) dichloride; In toluene; for 1h; Heating;

DOI:10.1021/ol035330d

upstream raw materials:

diazomethane

benzenehexacarboxylic acid

methanol

dimethyl acetylenedicarboxylate

Downstream raw materials:

Benzentris-

Refernces

• 1、 Brodt, Catherine,Niu, Shuqiang,Pritzkow, Hans,Stephan, Martin,Zenneck, Ulrich. "Reaktive ?-Komplexe der elektronenreichen Uebergangsmetalle. XIII. (η6-Hexalkylbenzol)(η4-naphthalin)eisen-Komplexe: Synthese, Eigenschaften, Struktur und Reaktivitaet". . p. 283 - 292. Retrieved 1993.
• 2、 Jarvis,A.C.,Kemmitt,R.D.W.. "-". . p. 121 - 138. Retrieved 1977.
• 3、 Desroy, Nicolas,Robert-Peillard, Fabien,Toueg, Julie,Henaut, Charlotte,Duboc, Romain,Rager, Marie-Noelle,Savignac, Monique,Genet, Jean-Pierre. "Synthesis of new polycyclic β-lactams via one-pot enyne metathesis and Diels-Alder reactions". . p. 2665 - 2672. Retrieved 2004.
• 4、 Stone, Matthew T.,Anderson, Harry L.. "Three-step synthesis of end-substituted pentacenes". . p. 9776 - 9778. Retrieved 2007.
• 5、 Bottari, Giovanni,Santos, Laura L.,Posadas, Cristina M.,Campos, Jesús,Mereiter, Kurt,Paneque, Margarita. "Reaction of [TpRh(C2H4)2] with Dimethyl Acetylenedicarboxylate: Identification of Intermediates of the [2+2+2] Alkyne and Alkyne–Ethylene Cyclo(co)trimerizations". . p. 13715 - 13723. Retrieved 2016.
• 6、 Tendera, Lukas,Helm, Moritz,Krahfuss, Mirjam J.,Kuntze-Fechner, Maximilian W.,Radius, Udo. "Case Study of N-iPr versus N-Mes Substituted NHC Ligands in Nickel Chemistry: The Coordination and Cyclotrimerization of Alkynes at [Ni(NHC)2]". supporting information. p. 17849 - 17861. Retrieved 2021/11/17.