Diphenyl(m-tolyl)phosphine

Base Information

• Chemical Name: Diphenyl(m-tolyl)phosphine
• CAS No.: 7579-70-6
• Molecular Formula: C19H17P
• Molecular Weight: 276.318
• NSC Number: 193777
• DSSTox Substance ID: DTXSID90307676
• Nikkaji Number: J1.398.242B
• Wikidata: Q82055177
• Mol file: 7579-70-6.mol

Synonyms:Diphenyl(m-tolyl)phosphine;7579-70-6;NSC193777;diphenyl-m-tolylphosphine;SCHEMBL50087;DTXSID90307676;(3-Methylphenyl)(diphenyl)phosphane;NSC-193777

Chemical Property of Diphenyl(m-tolyl)phosphine

Chemical Property:

• Vapor Pressure: 1.07E-05mmHg at 25°C
• Boiling Point: 382.1°Cat760mmHg
• Flash Point: 194.7°C
• Density: g/cm³
• XLogP3: 5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 276.106787540
• Heavy Atom Count: 20
• Complexity: 258

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)P(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Diphenyl(m-tolyl)phosphine

There total 11 articles about Diphenyl(m-tolyl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-Iodotoluene (625-95-6) + (diphenylphosphino)(p-tolyl)methanone (40841-62-1) → diphenyl (3‐methylphenyl) phosphine (7579-70-6)

Guidance literature:

With palladium diacetate; caesium carbonate; In toluene; at 80 ℃; for 12h; Sealed tube; Inert atmosphere;

DOI:10.1016/j.tetlet.2016.06.088

Reference yield: 82.0%

1-chloro-3-methylbenzene (108-41-8) + (trimethylsilyl)diphenylphosphine (17154-34-6) → diphenyl (3‐methylphenyl) phosphine (7579-70-6)

Guidance literature:

With bis(triphenylphosphine)nickel(II) chloride; potassium tert-butylate; In 1,4-dioxane; at 90 ℃; for 12h; Inert atmosphere;

DOI:10.1002/ejoc.201402660

Reference yield: 81.0%

3-Iodotoluene (625-95-6) + diphenylphosphane (829-85-6) → diphenyl (3‐methylphenyl) phosphine (7579-70-6)

Guidance literature:

With potassium acetate; In N,N-dimethyl acetamide; at 130 ℃; for 3h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.jorganchem.2018.04.018

upstream raw materials:

meta-bromotoluene

diphenylphosphane

3-Methylbenzonitrile

(trimethylsilyl)diphenylphosphine

Downstream raw materials:

3-(diphenylphosphoryl)benzoic acid

Refernces

• 1、 -. "Preparing method of triarylphosphine compound". Paragraph 0032; 0033; 0034; 0035. . Retrieved 2019/07/16.
• 2、 Fang, Zhiqiang,Cai, Mingzhong,Lin, Yang,Zhao, Hong. "An efficient heterogeneous cross-coupling of aryl iodides with diphenylphosphine catalyzed by copper (I) immobilized in MCM-41". . . Retrieved 2018/07/31.