1-(Pentylamino)-2-propanol

Base Information

• Chemical Name: 1-(Pentylamino)-2-propanol
• CAS No.: 41063-36-9
• Molecular Formula: C8H19NO
• Molecular Weight: 145.2426
• DSSTox Substance ID: DTXSID60961421
• Nikkaji Number: J2.254.575B
• Mol file: 41063-36-9.mol

Synonyms:1-(Pentylamino)-2-propanol;2-Propanol, 1-(pentylamino)-;41063-36-9;1-(pentylamino)propan-2-ol;SCHEMBL1140977;DTXSID60961421;AKOS009067584

Chemical Property of 1-(Pentylamino)-2-propanol

Chemical Property:

• Vapor Pressure: 0.0119mmHg at 25°C
• Boiling Point: 231.3°C at 760 mmHg
• Flash Point: 72.6°C
• Density: 0.868g/cm³
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 145.146664230
• Heavy Atom Count: 10
• Complexity: 66.3

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCNCC(C)O

Technology Process of 1-(Pentylamino)-2-propanol

There total 2 articles about 1-(Pentylamino)-2-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

n-Pentylamine (110-58-7) + methyloxirane (75-56-9,16033-71-9) → N-n-Pentyl-N-(2-hydroxypropyl)amin (41063-36-9)

Guidance literature:

scandium tris(trifluoromethanesulfonate); at 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2005.10.106

Reference yield:

n-Pentylamine (110-58-7) + 1-Chloro-2-propanol (127-00-4) → N-n-Pentyl-N-(2-hydroxypropyl)amin (41063-36-9)

Guidance literature:

DOI:10.1248/cpb.26.3891

Reference yield:

N-n-Pentyl-N-(2-hydroxypropyl)amin (41063-36-9) → N-amyl-N-(2-oxopropyl)nitrosamine (70103-58-1,74778-68-0,74778-87-3)

Guidance literature:

With pyridine; chromium(VI) oxide; In dichloromethane;

DOI:10.1248/cpb.26.3891

upstream raw materials:

n-Pentylamine

1-Chloro-2-propanol

methyloxirane

Downstream raw materials:

N-amyl-N-(2-oxopropyl)nitrosamine

Refernces

• 1、 Placzek, Andrew T.,Donelson, James L.,Trivedi, Rushi,Gibbs, Richard A.,De, Surya K.. "Scandium triflate as an efficient and useful catalyst for the synthesis of β-amino alcohols by regioselective ring opening of epoxides with amines under solvent-free conditions". . p. 9029 - 9034. Retrieved 2007/10/03.