Amylamine

Base Information

• Chemical Name: Amylamine
• CAS No.: 110-58-7
• Molecular Formula: C5H13N
• Molecular Weight: 87.1649
• Hs Code.: 29211990
• European Community (EC) Number: 203-780-2,932-628-4,935-734-9
• NSC Number: 7906
• UN Number: 1106
• UNII: E05QM3V8EF
• DSSTox Substance ID: DTXSID0021919
• Nikkaji Number: J1.978J
• Wikipedia: 1-Aminopentane
• Wikidata: Q766883
• Metabolomics Workbench ID: 146656
• Mol file: 110-58-7.mol

Synonyms:amylamine;amylamine hydrochloride;n-amylamine;n-amylamine hydrochloride;n-amylamine sulfate (2:1);n-pentylamine

Chemical Property of Amylamine

Chemical Property:

• Appearance/Colour: clear colourless to very slightly yellow liquid
• Vapor Pressure: 29.4mmHg at 25°C
• Melting Point: -55 °C(lit.)
• Refractive Index: n20/D 1.411(lit.)
• Boiling Point: 105.5 °C at 760 mmHg
• PKA: 10.63(at 25℃)
• Flash Point: 4.4 °C
• PSA: 26.02000
• Density: 0.755 g/cm³
• LogP: 1.83560
• Storage Temp.: Flammables area
• Sensitive.: Air Sensitive
• Solubility.: Soluble in alcohol, ether.
• Water Solubility.: soluble
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 87.104799419
• Heavy Atom Count: 6
• Complexity: 19.9
• Transport DOT Label: Flammable Liquid Corrosive

Purity/Quality:

98,99%, ^*data from raw suppliers

1-Pentylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C
• Hazard Codes: F,C
• Statements: 11-22-34-42/43-20/21/22-52/53
• Safety Statements: 16-26-36/37/39-45-33-61

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CCCCCN
• Recent EU Clinical Trials: Add-on Study of Olmesartan Medoxomil in Patients with Moderate to Severe Hypertension not Achieving Target Blood Pressure on
• Uses: Chemical intermediate, dyestuffs, rubber chemicals, insecticides, synthetic detergents, flotation agents, corrosion inhibitors, solvent, gasoline additive, pharmaceuticals. 1-Pentylamine is a useful reactant in organic synthesis. Amylamine is a general reagent used in functionalizing the target molecules with pentyl chain. It has also been used as a cosurfactant to increase the phase stability of the bilayer systems.

Technology Process of Amylamine

There total 100 articles about Amylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.5%

piperidine (110-89-4) + 1-Pentyl-1-hexylamine (41495-45-8) → 1-pentylpiperidine (10324-58-0) + 1-hexylpiperidine (7335-01-5) + hexan-1-amine (111-26-2) + dihexylamine (143-16-8) + n-Pentylamine (110-58-7) + Di-n-amylamine (2050-92-2)

Guidance literature:

With hydrogen; sulphidized CoO-MoO₃; at 300 ℃; for 1h; under 45003.6 Torr; Mechanism; Product distribution;

Reference yield:

complex of α-cyclodextrin with n-pentylamine → n-Pentylamine (110-58-7) + alpha cyclodextrin (10016-20-3)

Guidance literature:

With phosphate buffer; In water-d2; at 25 ℃; Equilibrium constant; Thermodynamic data; standard molar enthalpy Δ_rH⁰, standard molar Gibbs energy Δ_rG⁰, standard molar entropy Δ_rS⁰;

DOI:10.1021/jp962715n

Reference yield:

5-hydroxypentylamine (2508-29-4) → piperidin-2-one (675-20-7) + 4-pentenyl-1-amine (22537-07-1) + n-Pentylamine (110-58-7)

Guidance literature:

With cerium(IV) oxide; at 425 ℃; Inert atmosphere;

DOI:10.1016/j.apcata.2016.03.001

upstream raw materials:

pentyl-tetrahydropyran-2-yl-amine

O-Methylhydroxylamin

n-pentylmagnesium bromide

2,5-dimethyl-1-pentyl-1H-pyrrole

Downstream raw materials:

2-pentylaminoethanol

N-(1-pentanyl)benzamide

5-Hydroxy-2-pentyl-isoindole-1,3-dione

5-N-(n-Pentyl)-3-p-methoxyphenylglutaramic acid

Refernces

• 1、 Magnien,Baltzly. "-". . p. 2029. Retrieved 1958.
• 2、 Sehajpal, Pallvi,Kirar, Seema,Ghosh, Saptarshi,Banerjee, Uttam Chand. "Generation of novel family of reductases from PCR based library for the synthesis of chiral alcohols and amines". . p. 83 - 91. Retrieved 2018.
• 3、 Tanaka, Koji,Moriya, Makoto,Tanaka, Toshio. "Comparison of the Catalytic Behaviors of Single Cubane MoFe3S4 and Fe4S4 Clusters toward the Multi-electron Reduction of n-C5H11N3". . p. 373 - 376. Retrieved 1987.
• 4、 Fujita, Shu,Yamaguchi, Sho,Yamasaki, Jun,Nakajima, Kiyotaka,Yamazoe, Seiji,Mizugaki, Tomoo,Mitsudome, Takato. "Ni2P Nanoalloy as an Air-Stable and Versatile Hydrogenation Catalyst in Water: P-Alloying Strategy for Designing Smart Catalysts". . p. 4439 - 4446. Retrieved 2021.
• 5、 Scribner. "Azaprostanoids I. Synthesis of (RAC) 11 desoxy 12 azaprostanoids". . p. 3853 - 3856. Retrieved 1976.
• 6、 McGregor, James,Canning, Arran S.,Mitchell, Scott,Jackson, S. David,Gladden, Lynn F.. "The influence of carbon laydown on selectivity in the hydrogenation of pentenenitriles over supported-nickel catalysts". . p. 192 - 200. Retrieved 2010.
• 7、 Guo, Wanjun,Guo, Yong,Jia, Hongyan,Liu, Xiaohui,Pan, Hu,Wang, Yangang,Wang, Yanqin,Xia, Qineng. "Highly selective synthesis of primary amines from amide over Ru-Nb2O5 catalysts". . . Retrieved 2021/12/22.