Diamylamine

Base Information

• Chemical Name: Diamylamine
• CAS No.: 2050-92-2
• Molecular Formula: C10H23N
• Molecular Weight: 157.299
• Hs Code.: 2921199090
• European Community (EC) Number: 218-108-3
• ICSC Number: 0537
• NSC Number: 6329
• UN Number: 2841
• UNII: D67I8PN8UU
• DSSTox Substance ID: DTXSID4024931
• Nikkaji Number: J34.523G
• Wikidata: Q1964319
• ChEMBL ID: CHEMBL1232240
• Mol file: 2050-92-2.mol

Synonyms:Dipentylamine(6CI,7CI,8CI);Di-n-amylamine;Di-n-pentylamine;Dipentanamine;NSC 6329;

Chemical Property of Diamylamine

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 0.3 mm Hg ( 20 °C)
• Melting Point: -44 °C
• Refractive Index: n20/D 1.4258(lit.)
• Boiling Point: 203.791 °C at 760 mmHg
• PKA: 11.25±0.19(Predicted)
• Flash Point: 52.222 °C
• PSA: 12.03000
• Density: 0.777 g/cm³
• LogP: 3.34730
• Water Solubility.: Slightly soluble (0.1-1 g/100 mL)
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 8
• Exact Mass: 157.183049738
• Heavy Atom Count: 11
• Complexity: 53.9
• Transport DOT Label: Flammable Liquid Poison

Purity/Quality:

98% ^*data from raw suppliers

Diamylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T,N,C
• Statements: 23/24/25-34-37/38-24-22-50/53
• Safety Statements: 26-27-36/37/39-45-61-60

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CCCCCNCCCCC
• Inhalation Risk: No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
• Effects of Short Term Exposure: The substance is corrosive to the skin and eyes. The substance is severely irritating to the respiratory tract. Inhalation of the vapour or mist may cause lung oedema. The substance may cause effects on the central nervous system.
• Uses: Di-n-amylamine is manufactured from amyl chloride and ammonia. It is used in organic syntheses and as a solvent, rubber accelerator, flotation reagent, and corrosion inhibitor. Dipentylamine was used in the synthesis of new melt-spinnable polymeric precursor to boron nitride ceramic fibers. It was used to compose background electrolyte for the separation of linear alkylbenzene sulfonates by nonaqueous capillary electrophoresis. It was employed as organic additive in the synthesis of pure AlP04-H2 (aluminophosphate material).

Technology Process of Diamylamine

There total 53 articles about Diamylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

pentanonitrile (110-59-8) → Di-n-amylamine (2050-92-2)

Guidance literature:

With 10% rhodium on carbon; hydrogen; In cyclohexane; at 25 ℃; for 6h; under 760.051 Torr;

DOI:10.1021/acs.joc.7b01823

Reference yield: 90.0%

n-Pentylamine (110-58-7) → Di-n-amylamine (2050-92-2)

Guidance literature:

With [{^CyPN(H)P}Co(CH₂SiMe₃)]-BAr^F₄; In toluene; at 120 ℃; for 24h; Schlenk technique; Sealed tube;

DOI:10.1021/acscatal.6b02218

Reference yield: 88.0%

ethyl valerimidate (999-09-7) → Di-n-amylamine (2050-92-2)

Guidance literature:

With platinum on carbon; hydrogen; In ethanol; at 25 ℃; for 16h; under 30003 Torr; Autoclave;

upstream raw materials:

valeraldoxime

pentanonitrile

hexanedioic acid bis-pentylamide

N-benzyl-N-pentylpentan-1-amine

Downstream raw materials:

5-(4-chloro-phenyl)-N⁴,N⁴-dipentyl-pyrimidine-2,4,6-triyltriamine

dipentyl-phenethyl-amine

3-Dipentylamino-propionitril

N,N-dipentyl-2-chloroacetamide

Refernces

• 1、 Yoshimura, Masatoshi,Komatsu, Akira,Niimura, Masaru,Takagi, Yukio,Takahashi, Tohru,Ueda, Shun,Ichikawa, Tomohiro,Kobayashi, Yutaka,Okami, Hiroki,Hattori, Tomohiro,Sawama, Yoshinari,Monguchi, Yasunari,Sajiki, Hironao. "Selective Synthesis of Primary Amines from Nitriles under Hydrogenation Conditions". . p. 1726 - 1732. Retrieved 2018/03/21.
• 2、 Monguchi, Yasunari,Mizuno, Masahiro,Ichikawa, Tomohiro,Fujita, Yuki,Murakami, Eri,Hattori, Tomohiro,Maegawa, Tomohiro,Sawama, Yoshinari,Sajiki, Hironao. "Catalyst-Dependent Selective Hydrogenation of Nitriles: Selective Synthesis of Tertiary and Secondary Amines". . p. 10939 - 10944. Retrieved 2017/10/27.