2-bromo-1,1-diphenylethanol

Base Information

• Chemical Name: 2-bromo-1,1-diphenylethanol
• CAS No.: 950-16-3
• Molecular Formula: C14H13 Br O
• Molecular Weight: 277.161
• Mol file: 950-16-3.mol

Synonyms:Benzhydrol,a-(bromomethyl)- (6CI,7CI,8CI); 2,2-Diphenyl-2-hydroxyethyl bromide; NSC200678; NSC 72233

Chemical Property of 2-bromo-1,1-diphenylethanol

Chemical Property:

• Vapor Pressure: 4.83E-06mmHg at 25°C
• Boiling Point: 367.3°Cat760mmHg
• Flash Point: 182.4°C
• Density: 1.407g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-bromo-1,1-diphenylethanol

There total 8 articles about 2-bromo-1,1-diphenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,1-Diphenylethylene (530-48-3) → 2-bromo-1,1-diphenylethan-1-ol (950-16-3)

Guidance literature:

With N-Bromosuccinimide; water; In acetone; at 25 ℃; for 2h;

DOI:10.1016/j.bmc.2017.12.047

Reference yield: 59.0%

1,1-diphenylethanol (599-67-7) → 2-bromo-1,1-diphenylethan-1-ol (950-16-3)

Guidance literature:

With N-Bromosuccinimide; sodium dodecyl-sulfate; In water; at 95 - 100 ℃; for 7h; Green chemistry;

DOI:10.3390/molecules21101325

Reference yield: 5.0%

1,1-Diphenylethylene (530-48-3) → benzophenone (119-61-9) + 1,1-diphenyl-2-(phenylseleno)-ethan-1-ol (24946-01-8) + 2-bromo-1,1-diphenylethan-1-ol (950-16-3)

Guidance literature:

With Phenylselenyl bromide; oxygen; In dichloromethane; at -78 ℃; for 4h; Irradiation;

DOI:10.1016/S0040-4039(00)85518-5

upstream raw materials:

1,1-Diphenylethylene

N-bromoacetamide

Phenylselenyl bromide

1,1-diphenylethanol

Downstream raw materials:

1,1,2-Triphenylethanol

1,1-diphenyl-2-(piperazin-1-yl)ethan-1-ol

1-bromo-2,2-diphenylethylene

phenyl benzyl ketone

Refernces

• 1、 Parisi, Giovanna,Colella, Marco,Monticelli, Serena,Romanazzi, Giuseppe,Holzer, Wolfgang,Langer, Thierry,Degennaro, Leonardo,Pace, Vittorio,Luisi, Renzo. "Exploiting a beast in carbenoid chemistry: Development of a straightforward direct nucleophilic fluoromethylation strategy". supporting information. p. 13648 - 13651. Retrieved 2017/11/06.
• 2、 Yu, Lei,Ren, Lingfeng,Yi, Rong,Wu, Yulan,Chen, Tian,Guo, Rong. "Palladium-catalyzed reaction of olefins with PhI(OAc)TBAB system: An efficient and highly selective bisfunctionalization strategy". body text. p. 579 - 581. Retrieved 2011/04/18.